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Comparative genomics of yeast species: new insights into their biology

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Comparative genomics of yeast species: new insights into their biology

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dc.contributor.author Herrero, Enrique
dc.contributor.author Torre, María Ángeles de la
dc.contributor.author Valentín Gómez, Eulogio
dc.date.accessioned 2010-06-03T07:42:52Z
dc.date.available 2010-06-03T07:42:52Z
dc.date.issued 2003
dc.identifier.citation Herrero, Enrique; Torre, María Ángeles de la; Valentin Gomez, Eulogio. Comparative genomics of yeast species: new insights into their biology. International Microbiology, 2003, 6: 183–190 en
dc.identifier.uri http://hdl.handle.net/10550/12853
dc.description.abstract The genomes of two hemiascomycetous yeasts (Saccharomyces cerevisiae and Candida albicans) and one archiascomycete (Schizosaccharomyces pombe) have been completely sequenced and the genes have been annotated. In addition, the genomes of 13 more Hemiascomycetes have been partially sequenced. The amount of data thus obtained provides information on the evolutionary relationships between yeast species. In addition, the differential genetic characteristics of the microorganisms explain a number of distinctive biological traits. Gene order conservation is observed between phylogenetically close species and is lost in distantly related species, probably due to rearrangements of short regions of DNA. However, gene function is much more conserved along evolution. Compared to S. cerevisiae and S. pombe, C. albicans has a larger number of specific genes, i.e., genes not found in other organisms, a fact that can account for the biological characteristics of this pathogenic dimorphic yeast which is able to colonize a large variety of environments. en
dc.language.iso en en
dc.subject Saccharomyces cerevisiae; Candida albicans; Schizosaccharomyces pombe; Hemiascomycetes; Comparative genomics en
dc.title Comparative genomics of yeast species: new insights into their biology en
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS DE LA VIDA::Microbiología ::Metabolismo microbiano en
dc.identifier.doi 10.1007/s10123-003-0132-1 en
dc.identifier.idgrec 003930 en
dc.type.hasVersion VoR es_ES
dc.identifier.url http://www.im.microbios.org/articles0203/2003/september/06%20Herrero.pdf en

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