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Birth weight influences blood pressure values and variability in children and adolescents

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Birth weight influences blood pressure values and variability in children and adolescents

dc.contributor.author	Lurbe i Ferrer, Empar
dc.contributor.author	Torró Doménech, María Isabel
dc.contributor.author	Rodriguez, Concepción
dc.contributor.author	Alvarez, Vicente
dc.contributor.author	Redón i Más, Josep
dc.date.accessioned	2010-07-30T10:20:57Z
dc.date.available	2010-07-30T10:20:57Z
dc.date.issued	2001
dc.identifier.citation	LURBE FERRER, Maria Desamparados ; Torró Doménech, María Isabel ; Rodriguez, Concepción ; Alvarez, Vicente ; Redon Mas, Josep, 2001, Birth weight influences blood pressure values and variability in children and adolescents, Hypertension, vol. 38, no. 3, p. 389-393	en
dc.identifier.uri	http://hdl.handle.net/10550/16723
dc.description.abstract	The objective of the present study was to assess the relationships between birth weight and the values and variability of ambulatory blood pressure. Six hundred thirty healthy children (369 girls) age 4 to 18 years (mean, 9.9 years) born at term after a normotensive pregnancy were included. The subjects were divided into 5 groups according to birth weight. For each subject, a 24-hour ambulatory blood pressure monitoring was performed according to the protocol designed. Average and variability (estimated as the standard deviation) of ambulatory blood pressure and heart rate were calculated separately for 24-hour, daytime, and nighttime periods. When values were adjusted for gender, current age, weight, and height, children with the lowest birth weights had the highest ambulatory blood pressure values and variability, whereas no differences in heart rate were observed. Multiple regression analysis showed that although current weight was the strongest predictor for 24-hour systolic blood pressure (P<0.001), there was also an independent and significant inverse relationship for birth weight (P<0.002) after controlling for gender, current age, and height. Likewise, birth weight was independently and inversely correlated with 24-hour systolic blood pressure variability (P<0.03). In conclusion, children who had lower birth weights tended to have not only the highest blood pressure values but also the highest blood pressure variability, independent of the increases in ambulatory blood pressure values. Knowing that high blood pressure variability is at least partially independent of blood pressure values, the importance of this variability on further blood pressure rises and/or on vascular damage later in life needs to be assessed in future studies.	en
dc.language.iso	en	en
dc.subject	Blood pressure ; Blood pressure monitoring, ambulatory ; Hypertension, essential ; Children ; Birth weight	en
dc.title	Birth weight influences blood pressure values and variability in children and adolescents	en
dc.type	journal article	es_ES
dc.subject.unesco	UNESCO::CIENCIAS MÉDICAS	en
dc.subject.unesco	UNESCO::CIENCIAS MÉDICAS ::Medicina interna	en
dc.identifier.idgrec	018509	en
dc.type.hasVersion	VoR	es_ES
dc.identifier.url	http://hyper.ahajournals.org/cgi/reprint/38/3/389	en