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Toluidine blue staining as an adjunctive tool for early diagnosis of dysplastic changes in the oral mucosa

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Toluidine blue staining as an adjunctive tool for early diagnosis of dysplastic changes in the oral mucosa

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dc.contributor.author Pallagatti, Shambulingappa es
dc.contributor.author Sheikh, Soheyl es
dc.contributor.author Aggarwal, Amit es
dc.contributor.author Gupta, Deepak es
dc.contributor.author Singh, Ravinder es
dc.contributor.author Handa, Roopika es
dc.contributor.author Kaur, Simranpreet es
dc.contributor.author Mago, Jyoti es
dc.date.accessioned 2014-05-22T09:38:39Z
dc.date.available 2014-05-22T09:38:39Z
dc.date.issued 2013 es
dc.identifier.citation Pallagatti, Shambulingappa ; Sheikh, Soheyl ; Aggarwal, Amit ; Gupta, Deepak ; Singh, Ravinder ; Handa, Roopika ; Kaur, Simranpreet ; Mago, Jyoti. Toluidine blue staining as an adjunctive tool for early diagnosis of dysplastic changes in the oral mucosa. En: Journal of Clinical and Experimental Dentistry, 2013, Vol. 5, No. 4: 187-191 es
dc.identifier.uri http://hdl.handle.net/10550/35339
dc.description.abstract Prognosis of oropharyngeal squamous cell carcinoma depends on early diagnosis, despite advanced surgical techniques, the 5-year survival rate remains ~40-50%. Unfortunately, it is usually detected when it becomes symptomatic. This requires treatment which gives rise to a high rate of morbidity and mortality and, furthermore, early detection of oro-pharyngeal pre-malignant lesions is important to improve the survival rate and quality of life. Since dysplasia and in situ carcinoma contain much more DNA and RNA than the normal surrounding epithelium, the use of in vivo staining, by means of toluidine blue dye, is based on the fact that it is an acidophilic dye that selectively stains acidic tissue components such as DNA and RNA. Toluidine blue staining is considered to be sensitive in identifying early oro-pharyngeal premalignant and malignant lesions. In the present study, the use of toluidine blue staining was taken into consideration to identify clinically doubtful oro-pharyngeal lesions and to compare toluidine blue stain and with the histological evaluation. en_US
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Toluidine blue staining as an adjunctive tool for early diagnosis of dysplastic changes in the oral mucosa es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.type.hasVersion VoR es_ES

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