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Frequency of micronucleus in oral epithelial cells after exposure to mate-tea in healthy humans

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Frequency of micronucleus in oral epithelial cells after exposure to mate-tea in healthy humans

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dc.contributor.author Bortoluzzi, Marcelo Carlos es
dc.contributor.author Campagnoli, Eduardo-Baulm es
dc.contributor.author Milan, José-Ricaon es
dc.contributor.author Reinheimer, Angélica es
dc.contributor.author Masson, Maicon es
dc.contributor.author Capella, Diogo-Lenzi es
dc.date.accessioned 2015-01-08T12:30:59Z
dc.date.available 2015-01-08T12:30:59Z
dc.date.issued 2014 es
dc.identifier.citation Bortoluzzi, Marcelo Carlos ; Campagnoli, Eduardo-Baulm ; Milan, José-Ricaon ; Reinheimer, Angélica ; Masson, Maicon ; Capella, Diogo-Lenzi. Frequency of micronucleus in oral epithelial cells after exposure to mate-tea in healthy humans. En: Medicina oral, patología oral y cirugía bucal. Ed inglesa, 2014, Vol. 19, No. 4: 345-349 es
dc.identifier.uri http://hdl.handle.net/10550/41120
dc.description.abstract Objectives: The aim of this study was to evaluate the possibility of technique simplification for cytology slides in order to evaluate the frequency of micronuclei (FMic) and conduct a experiment looking to know the FMic of oral epithelial cells of healthy volunteers exposed to mate tea (Ilex paraguarariensis). Material and Methods: This is a laboratorial and nonrandomized trial (quasi-experiment), where the nonusers subjects were exposed to mate-tea, consumed in the traditional way, two drinks, two times a day for a single week. Two cytology of exfoliated epithelial cells were obtained before and after the mate tea exposition. Results: The sample was composed by 10 volunteers. The age ranged from 18 to 33 years (Mean 23; SD5.5). The use of mate tea did not showed significant variation in the FMic (Wilcoxon Signed Ranks Test p = .24). Conclusions: The proposed technique simplification showed to be reliable, without losses when compared to the conventional technique and with the advantage of eliminate toxic substances, becoming simple and practical tool for research in dentistry. The acute exposure to mate tea did not induce an increase of FMic in exfoliated buccal cells of healthy nondrinkers and nonsmokers subjects and may not have genotoxic effect. More human studies are needed before a conclusion can be made on the oral carcinogenic risk of mate tea to humans. en_US
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Frequency of micronucleus in oral epithelial cells after exposure to mate-tea in healthy humans es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.type.hasVersion VoR es_ES
dc.identifier.url http://www.medicinaoral.com/pubmed/medoralv19_i4_p345.pdf es

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