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Ghost cell odontogenic carcinoma: a rare case report and review of literature

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Ghost cell odontogenic carcinoma: a rare case report and review of literature

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dc.contributor.author Martos Fernández, Míriam es
dc.contributor.author Alberola Ferranti, Margarita es
dc.contributor.author Hueto Madrid, Juan Antonio es
dc.contributor.author Bescós Atín, Socorro es
dc.date.accessioned 2015-01-20T09:16:42Z
dc.date.available 2015-01-20T09:16:42Z
dc.date.issued 2014 es
dc.identifier.citation Martos Fernández, Míriam ; Alberola Ferranti, Margarita ; Hueto Madrid, J.A. ; Bescós Atín, Socorro. Ghost cell odontogenic carcinoma: a rare case report and review of literature. En: Journal of Clinical and Experimental Dentistry, 2014, Vol. 6, No. 5: 602-606 es
dc.identifier.uri http://hdl.handle.net/10550/41322
dc.description.abstract Objectives: Ghost cell odontogenic carcinoma is a rare condition characterized by ameloblastic-like islands of epithelial cells with aberrant keratinitation in the form of Ghost cell with varying amounts of dysplastic dentina. Material and Methods: We report a case of a 70 year-old woman with a rapid onset of painful swelling right maxillary tumor. Magnetic resonance showed a huge tumor dependent on the right half of the right hard palate with invasion of the pterygoid process and focally to the second branch of the trigeminal. Radiological stage was T4N0. The patient underwent a right subtotal maxillectomy with clear margins. Adjuvant radiotherapy was given. The patient was free of residual or recurrent disease 12 months after surgery. Results: The tumor was 3,9cm in diameter. It was spongy and whitish gray. Microscopically the tumor was arranged in nets and trabeculae, occasionally forming palisade. Tumoral cells had clear cytoplasm with vesicular nuclei. There was atipia and mitosi with vascular and perineural invasion. The excised tumor was diagnosed as a GCOC. Conclusions: Ghost cell carcinoma is a rare odontogenic carcinoma. Its course is unpredictable, ranging from locally invasive tumors of slow growth to highly aggressive and infiltrative ones. Wide surgical excision with clean margins is the treatment of choice although its combination with postoperative radiation therapy, with or without chemotherapy, remains controversial. en_US
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Ghost cell odontogenic carcinoma: a rare case report and review of literature es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.type.hasVersion VoR es_ES

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