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Moxifloxacin versus Clindamycin/Ceftriaxone in the management of odontogenic maxillofacial infectious processes: a preliminary, intrahospital, controlled clinical trial

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Moxifloxacin versus Clindamycin/Ceftriaxone in the management of odontogenic maxillofacial infectious processes: a preliminary, intrahospital, controlled clinical trial

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dc.contributor.author Gómez Arámbula, Hansel es
dc.contributor.author Hidalgo Hurtado, Antonio es
dc.contributor.author Rodríguez Flores, Rosaura es
dc.contributor.author González Amaro, Ana María es
dc.contributor.author Garrocho Rangel, Arturo es
dc.contributor.author Pozos Guillén, Amaury de Jesús es
dc.date.accessioned 2016-01-20T12:12:22Z
dc.date.available 2016-01-20T12:12:22Z
dc.date.issued 2015 es
dc.identifier.citation Gómez Arámbula, Hansel ; Hidalgo Hurtado, Antonio ; Rodríguez Flores, Rosaura ; González Amaro, Ana María ; Garrocho Rangel, Arturo ; Pozos Guillén, Amaury de Jesús. Moxifloxacin versus Clindamycin/Ceftriaxone in the management of odontogenic maxillofacial infectious processes: a preliminary, intrahospital, controlled clinical trial. En: Journal of Clinical and Experimental Dentistry, 2015, Vol. 7, No. 5: 634-639 es
dc.identifier.uri http://hdl.handle.net/10550/50180
dc.description.abstract Background: The aim of this study was to compare the days of hospitalization length between patients treated with Moxifloxacin with that of patients treated with a Clindamycin/Ceftriaxone combination and additionally, to isolate and identify the oral pathogens involved in orofacial odontogenic infections. Material and Methods: A pilot-controlled-clinical-trial was carried out on hospitalized patients with cervicofacial odontogenic abscesses or cellulitis, who were randomly asigned to two study groups: 1) patients who received Moxifloxacin, and 2) patients receiving Clindamycin/Ceftriaxone combination. Infiltrate samples were collected through transdermic or transmucosal punction and later cultured on a media specific for aerobic and anaerobic microorganisms. Mean hospitalization duration in days until hospital discharge and susceptibility assessment in rates were established. Results: Mean hospitalization time in days of patients treated with Moxifloxacin was 7.0 ± 1.6 days, while in the Clindamycin/Ceftriaxone group, this was 8.4 ± 1.8 days, although significant difference could not be demonstrated ( p =0.074). A total of 43 strains were isolated, all of these Gram-positive. These strains appeared to be highly sen - sitive to Moxifloxacin (97.5%) and Ceftriaxone (92.5%). Conclusions: Moxifloxacin and Ceftriaxone appear to be potential convenient and rational alternatives to traditional antibiotics, for treating severe odontogenic infections, in conjunction with surgical extraoral incision, debridement, and drainage. en_US
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Moxifloxacin versus Clindamycin/Ceftriaxone in the management of odontogenic maxillofacial infectious processes: a preliminary, intrahospital, controlled clinical trial es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.type.hasVersion VoR es_ES

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