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Lack of evidence of hepatitis in patients with oral lichen planus in China: a case control study

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Lack of evidence of hepatitis in patients with oral lichen planus in China: a case control study

dc.contributor.author	Song, Jiangyuan	es
dc.contributor.author	Zhang, Zhihui	es
dc.contributor.author	Ji, Xiaoli	es
dc.contributor.author	Su, Sha	es
dc.contributor.author	Liu, Xiaodan	es
dc.contributor.author	Xu, Si	es
dc.contributor.author	Han, Ying	es
dc.contributor.author	Mu, Dongdong	es
dc.contributor.author	Liu, Hongwei	es
dc.date.accessioned	2016-07-26T11:49:35Z
dc.date.available	2016-07-26T11:49:35Z
dc.date.issued	2016	es
dc.identifier.citation	Song, Jiangyuan ; Zhang, Zhihui ; Ji, Xiaoli ; Su, Sha ; Liu, Xiaodan ; Xu, Si ; Han, Ying ; Mu, Dongdong ; Liu, Hongwei. Lack of evidence of hepatitis in patients with oral lichen planus in China: a case control study. En: Medicina oral, patología oral y cirugía bucal. Ed inglesa, 2016, : 161-	es
dc.identifier.uri	http://hdl.handle.net/10550/54737
dc.description.abstract	Background: China has been one of the countries with high prevalence of chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) liver disease. And lichen planus is an extrahepatic manifestation of patients with chronic HCV infection. This case-control study was conducted to investigate the relationship between oral lichen planus (OLP) and HBV/HCV infection in China. Material and Methods: A total of 776 patients, including 150 patients with OLP (Group OLP), 429 inpatients from the Trauma Ward of Oral and Maxillofacial Surgery Department (Group A), 110 patients with other oral mucosal diseases, but without a reported association with HCV infection (Group B) and 87 patients with oral lichenoid lesion (Group OLL), were compared with their seroprevalence of anti-HCV antibody (HCVAb), hepatitis B surface antigen (HBsAg) and the parameters of liver functions. Moreover, the clinical characteristics of OLP were also observed, such as gender, age, chief complaint, course of the disease, clinical type, sites involved and so on. Results: The positive rates of HCVAb and HBsAg in OLP patients were 0.7% and 4%, respectively. Neither HCVAb nor HBsAg was associated with OLP as demonstrated by both the univariate and the multivariate analyses. The clinical features and liver functions of OLP patients with negative or positive HBsAg were nearly the same. Conclusions: Our findings verify that there is no association between OLP and hepatitis and there is no need to run a screening test for HCV or HBV in OLP patients in China	en_US
dc.relation		es
dc.subject	Odontología	es
dc.subject	Ciencias de la salud	es
dc.title	Lack of evidence of hepatitis in patients with oral lichen planus in China: a case control study	es
dc.type	journal article	es_ES
dc.subject.unesco	UNESCO::CIENCIAS MÉDICAS	es
dc.type.hasVersion	VoR	es_ES