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Effect of nonsurgical periodontal treatment in patients with periodontitis and rheumatoid arthritis: a systematic review

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Effect of nonsurgical periodontal treatment in patients with periodontitis and rheumatoid arthritis: a systematic review

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dc.contributor.author Silvestre Donat, Francisco Javier es
dc.contributor.author Silvestre Rangil, Javier es
dc.contributor.author Bagán Debón, Leticia es
dc.contributor.author Bagán Sebastián, José Vicente es
dc.date.accessioned 2016-07-26T11:59:43Z
dc.date.available 2016-07-26T11:59:43Z
dc.date.issued 2016 es
dc.identifier.citation Silvestre Donat, Francisco Javier ; Silvestre Rangil, Javier ; Bagán Debón, Leticia María; Bagán Sebastián, José Vicente. Effect of nonsurgical periodontal treatment in patients with periodontitis and rheumatoid arthritis: a systematic review. En: Medicina oral, patología oral y cirugía bucal. Ed inglesa, 2016, Vol. 21, No. 3: 349- es
dc.identifier.uri http://hdl.handle.net/10550/54779
dc.description.abstract Background: Periodontitis has been regarded as a potential risk factor for rheumatoid arthritis (RA). A systematic review is made to determine whether nonsurgical periodontal treatment in patients with RA offers benefits in terms of the clinical activity and inflammatory markers of the disease. Material and Methods: A search was made of the Medline-PubMed, Cochrane, Embase and Scopus databases to identify studies on the relationship between the two disease processes, and especially on the effects of nonsurgical treatment in patients of this kind. The search was based on the following keywords: rheumatoid arthritis AND periodontitis (MeSH), rheumatoid arthritis AND periodontal treatment . Results: Eight articles on the nonsurgical treatment of patients with periodontitis and RA were finally included in the study. All of them evaluated clinical (DAS28) and laboratory test activity (ESR, CRP, IL-6, TNFα) before and after treatment. A clear decrease in DAS28 score and ESR was recorded, while other parameters such as CRP, IL-6 and TNFα showed a nonsignificant tendency to decrease as a result of treatment. Conclusions: Nonsurgical treatment improved the periodontal condition of patients with periodontitis and RA, with beneficial effects upon the clinical and laboratory test parameters (DAS28 and ESR), while other inflammatory markers showed a marked tendency to decrease. However, all the studies included in the review involved small samples sizes and follow-up periods of no more than 6 months. Larger and particularly longitudinal studies are therefore needed to more firmly establish possible significant relations between the two disease processes. en_US
dc.relation es
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Effect of nonsurgical periodontal treatment in patients with periodontitis and rheumatoid arthritis: a systematic review es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.idgrec 112791
dc.type.hasVersion VoR es_ES

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