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Leukocyte adhesion deficiency type I - a focus on oral disease in a young child

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Leukocyte adhesion deficiency type I - a focus on oral disease in a young child

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dc.contributor.author Yashoda Devi, Bhoom Kantharaj es
dc.contributor.author Rakesh, Nagaraju es
dc.contributor.author Devaraju, Devaiah es
dc.contributor.author Santana, Nataraj es
dc.date.accessioned 2017-07-26T12:32:07Z
dc.date.available 2017-07-26T12:32:07Z
dc.date.issued 2011 es
dc.identifier.citation Yashoda Devi, Bhoom Kantharaj ; Rakesh, Nagaraju ; Devaraju, Devaiah ; Santana, Nataraj. Leukocyte adhesion deficiency type I - a focus on oral disease in a young child. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 16 2 2011: 5- es
dc.identifier.uri http://hdl.handle.net/10550/60150
dc.description.abstract This paper presents a case of the moderate form of Leukocyte adhesion deficiency type 1 (LAD-1) in a 4 year-old boy. LAD-1 is a rare, inherited immunodeficiency that affects 1 in 1 million people yearly. Affected patients are susceptible to recurrent bacterial and fungal infections, impaired pus formation and delayed wound healing. In the oral clinical finding, more important is a generalized prepuberal periodontitis that can affect the primary and permanent dentitions. For this reason cooperation between dentists and pediatricians is essential in these patients. Evaluating immune system in these patients included peripheral blood leukocyte counts, measurement of serum immunoglobulin levels, assessment of complement level and function, flow cytometric analysis of lymphocyte subsets, and tests of phagocytic function (nitrobluetetrazolium test (NBT)). In families with known molecular defect, an earlier prenatal diagnosis is possible by chorionic villi biopsy. The most important focus should be to control infections. Treatment includes systemic antibiotics and in many cases bone marrow transplantation. es
dc.title Leukocyte adhesion deficiency type I - a focus on oral disease in a young child es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.16.e153 es
dc.type.hasVersion VoR es_ES

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