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Correlation of serum and salivary CA15-3 levels in patients with breast cancer

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Correlation of serum and salivary CA15-3 levels in patients with breast cancer

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dc.contributor.author Agha-Hosseini, Farzaneh es
dc.contributor.author Mirzaii Dizgah, Iraj es
dc.contributor.author Rahimi, Asieh es
dc.date.accessioned 2017-09-07T08:55:23Z
dc.date.available 2017-09-07T08:55:23Z
dc.date.issued 2009 es
dc.identifier.citation Agha-Hosseini, Farzaneh ; Mirzaii Dizgah, Iraj ; Rahimi, Asieh. Correlation of serum and salivary CA15-3 levels in patients with breast cancer. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 14 10 2009: 6- es
dc.identifier.uri http://hdl.handle.net/10550/60601
dc.description.abstract Objectives: The aim of this study was to assess the relationship between serum and saliva levels of cancer antigen (CA) 15-3 and to compare them between women with and without breast cancer. Study design: A case-control study was carried out on 61 women aged 28-69 years, including women with and without breast cancer (26 as part of the case study and 35 as part of the control group) conducted at the Emam Khomeini Hospital, Tehran University of Medical Sciences. CA15-3 levels were assayed in serum and unstimulated whole saliva by EIA. Unpaired t-test, one-way ANOVA and Pearson correlation were used as statistical analysis. Results: The salivary and serological levels of CA15-3 in the cancer patients were significantly higher (P <0.01) than the salivary and serum levels of healthy controls. They were also higher in stage 2 than in stage 1 in cancer patients. However, the saliva flow rate was significantly lower in the cancer patients (P <0.01). There was a significant positive correlation between serum and saliva CA15-3 concentration (r = 0.614) and also between serum concentration and saliva output of CA15-3 (r = 0.541). Conclusion: The results of the study suggest that salivary CA15-3 may have potential use in the initial detection of breast cancer in women. es
dc.title Correlation of serum and salivary CA15-3 levels in patients with breast cancer es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.14.e521 es
dc.type.hasVersion VoR es_ES

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