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Structural and functional salivary disorders in type 2 diabetic patients

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Structural and functional salivary disorders in type 2 diabetic patients

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dc.contributor.author Carda Batalla, María del Carmen es
dc.contributor.author Mosquera Lloreda, Nezly es
dc.contributor.author Salom, Lucas es
dc.contributor.author Gómez de Ferraris, María Elsa es
dc.contributor.author Peydró Olaya, Amando es
dc.date.accessioned 2017-11-28T13:33:49Z
dc.date.available 2017-11-28T13:33:49Z
dc.date.issued 2006 es
dc.identifier.citation Carda Batalla, María del Carmen ; Mosquera Lloreda, Nezly ; Salom, Lucas ; Gómez de Ferraris, María Elsa ; Peydró Olaya, Amando. Structural and functional salivary disorders in type 2 diabetic patients . En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 11 4 2006: 3- es
dc.identifier.uri http://hdl.handle.net/10550/63384
dc.description.abstract Diabetes mellitus type 2 is the most common metabolic disorder and it causes an important morbimortality. The structural modifications in the parotid gland (sialosis) had already been described in these patients and could result in variations in the salivary composition, as well as an increase in periodontal and dental pathology. Objectives: to compare the biochemical findings in the saliva and to correlate these biochemical disturbances with the morphologic findings previously described. Patients and methods: clinical information were gathered about 33 patients, 17 had type 2 diabetes. Samples of whole saliva were obtained for biochemical analysis and serum samples to determine metabolic control. Results: in the diabetics saliva we found urea and total proteins increased and reduced levels of microalbumina. Salivary glucose was only augmented in patients with poor metabolic control. Clinical symptoms of xerostomia were present in 76,4% and dental and periodontal disease in 100%. The parotid gland was characterised by the presence of small acini, lipid intracytoplasmic droplets, as well as adipose stroma infiltration. The acinar cytoqueratins? expression was heterogeneous and very positive in the hyperplasic ducts. Conclusions: these biochemical disorders in the saliva of the type 2 diabetic patients would be related with the structural changes previously observed in parotid glands. es
dc.title Structural and functional salivary disorders in type 2 diabetic patients es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi es
dc.type.hasVersion VoR es_ES

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