recurrences following CCH treatment of Dupuytren?s disease are controversial and sometimes normal pathological anatomy is distorted. Our study aims to evaluate the presence of possible alterations of the disease at pathological level on samples of recurrence of Dupuytren?s disease (CCH vs fasciectomy). Methods: prospective, blind study for pathological and statistical analysis of patients who underwent fasciectomy due to recurrence of Dupuytren?s disease after previous treatment with collagenase or previous fasciectomy. Pathological study with H / E and immunohistochemistry. Results: a total of 8 patients were included (4 with previous treatment with CCH and 4 with fasciectomy). There were no significant differences in anatomopathological or inmonuhistochemical analysis. Conclusions: histologically, recurrences of Dupuytren Disease after fasciectomy or collagenase treatment are indistinguishable. The presentation of macroscopic forms other than those seen in fasciectomy is possible.