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Therapeutic tools for oral candidiasis : current and new antifungal drugs

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Therapeutic tools for oral candidiasis : current and new antifungal drugs

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dc.contributor.author Quindós Andrés, Guillermo es
dc.contributor.author Gil Alonso, Sandra es
dc.contributor.author Marcos Arias, Cristina es
dc.contributor.author Sevillano Peña, Elena es
dc.contributor.author Mateo, Estibaliz es
dc.contributor.author Jaureguizar Albonigamayor, Nerea es
dc.contributor.author Eraso Barrio, Elena es
dc.date.accessioned 2019-04-15T10:50:09Z
dc.date.available 2019-04-15T10:50:09Z
dc.date.issued 2019 es
dc.identifier.citation Quindós Andrés, Guillermo ; Gil Alonso, Sandra ; Marcos Arias, Cristina ; Sevillano Peña, Elena ; Mateo, Estibaliz ; Jaureguizar Albonigamayor, Nerea ; Eraso Barrio, Elena. Therapeutic tools for oral candidiasis : current and new antifungal drugs. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 24 2 2019: 10- es
dc.identifier.uri http://hdl.handle.net/10550/69960
dc.description.abstract Candidiasis is one of the most common opportunistic oral infections that presents different acute and chronic clinical presentations with diverse diagnostic and therapeutic approaches. The present study carries out a bibliographic review on the therapeutic tools available against oral candidiasis and their usefulness in each clinical situation. Recent studies on treatment of oral candidiasis were retrieved from PubMed and Cochrane Library. Nystatin and miconazole are the most commonly used topical antifungal drugs. Both antifungal drugs are very effective but need a long time of use to eradicate the infection. The pharmacological presentations of miconazole are more comfortable for patients but this drug may interact with other drugs and this fact should be assessed before use. Other topical alternatives for oral candidiasis, such as amphotericin B or clotrimazole, are not available in many countries. Oral fluconazole is effective in treating oral candidiasis that does not respond to topical treatment. Other systemic treatment alternatives, oral or intravenous, less used are itraconazole, voriconazole or posaconazole. Available novelties include echinocandins (anidulafungin, caspofungin) and isavuconazole. Echinocandins can only be used intravenously. Isavuconazole is available for oral and intravenous use. Other hopeful alternatives are new drugs, such as ibrexafungerp, or the use of antibodies, cytokines and antimicrobial peptides. Nystatin, miconazole, and fluconazole are very effective for treating oral candidiasis. There are systemic alternatives for treating recalcitrant infections, such as the new triazoles, echinocandins, or lipidic presentations of amphotericin B. es
dc.title Therapeutic tools for oral candidiasis : current and new antifungal drugs es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.22978 es
dc.type.hasVersion VoR es_ES

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