NAGIOS: RODERIC FUNCIONANDO

Diarylprolinol as a Ligand for Enantioselective Alkynylation of Cyclic Imines

Repositori DSpace/Manakin

dc.contributor.author	De Munck, Lode
dc.contributor.author	Monleón Ventura, Alicia
dc.contributor.author	Vila Descals, Carlos
dc.contributor.author	Pedro, José Ramón
dc.date.accessioned	2020-03-27T11:23:42Z
dc.date.available	2020-03-27T11:23:42Z
dc.date.issued	2017
dc.identifier.citation	De Munck, Lode Monleón Ventura, Alicia Vila Descals, Carlos Pedro, José Ramón 2017 Diarylprolinol as a Ligand for Enantioselective Alkynylation of Cyclic Imines Advanced Synthesis & Catalysis 359 9 1582 1587
dc.identifier.uri	https://hdl.handle.net/10550/73691
dc.description.abstract	An easily accessible prolinol derived ligand, (S)‐bis(3,5‐bis(trifluoromethyl)phenyl)(pyrrolidin‐2‐yl)methanol, has been efficiently applied in the catalytic enantioselective addition of terminal alkynes to cyclic imines using dimethylzinc (Me2Zn) under mild reaction conditions. The developed catalytic system led to chiral propargylic sulfamidates with high yields (up to 97%) and excellent enantioselectivities (up to 97% ee).
dc.language.iso	eng
dc.relation.ispartof	Advanced Synthesis & Catalysis, 2017, vol. 359, num. 9, p. 1582-1587
dc.subject	Catàlisi
dc.subject	Alcohols
dc.subject	Química orgànica
dc.title	Diarylprolinol as a Ligand for Enantioselective Alkynylation of Cyclic Imines
dc.type	journal article	es_ES
dc.date.updated	2020-03-27T11:23:42Z
dc.identifier.doi	10.1002/adsc.201601379
dc.identifier.idgrec	117129
dc.rights.accessRights	open access	es_ES