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The impact of liquid-pressurized extracts of Spirulina, Chlorella and Phaedactylum tricornutum on in vitro antioxidant, antiinflammatory and bacterial growth effects and gut microbiota modulation

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The impact of liquid-pressurized extracts of Spirulina, Chlorella and Phaedactylum tricornutum on in vitro antioxidant, antiinflammatory and bacterial growth effects and gut microbiota modulation

dc.contributor.author	Zhou, Jianjun
dc.contributor.author	Wang, Min
dc.contributor.author	Bäuerl, Christine
dc.contributor.author	Cortés Macías, Erika
dc.contributor.author	Calvo Lerma, Joaquim
dc.contributor.author	Collado Amores, María Carmen
dc.contributor.author	Barba Orellana, Francisco José
dc.date.accessioned	2022-11-28T14:19:16Z
dc.date.available	2022-11-28T14:19:16Z
dc.date.issued	2023
dc.identifier.citation	Zhou, Jianjun Wang, Min Bäuerl, Christine Cortés Macías, Erika Calvo Lerma, Joaquim Collado Amores, María Carmen Barba Orellana, Francisco José 2023 The impact of liquid-pressurized extracts of Spirulina, Chlorella and Phaedactylum tricornutum on in vitro antioxidant, antiinflammatory and bacterial growth effects and gut microbiota modulation Food Chemistry 401 134083
dc.identifier.uri	https://hdl.handle.net/10550/84597
dc.description.abstract	The impact of Spirulina, Chlorella and Phaeodactylum tricornutum (P. tricornutum) microalgal extracts obtained by pressurized liquid extraction (PLE) on antioxidant and anti-inflammatory activities, microbial growth and in vitro gut microbiota composition was evaluated. PLE, compared to conventional extraction, led to a significant (p < 0.05) increase in proteins, carbohydrates, polyphenols, and antioxidant capacities of the three microalgal extracts. Moreover, Spirulina and P. tricornutum extracts significantly (p < 0.05) reduced the in vitro activation of the inflammatory NF-κB pathway. The microalgal extracts had also an inhibitory effect on the pathogenic bacteria while potential beneficial Lactobacillus and Bifidobacterium strains increased growth. The effects of microalgal extracts on specific bacterial groups were analyzed by quantitative PCR technology, and bacterial gene copy numbers were affected by in vitro digestion process and colonic fermentation time. GC-MS results showed that microalgal biomolecules' digestion promoted the release of short-chain fatty acids (SCFAs) during in vitro colonic microbiota fermentation, particularly acetic, butanoic and propanoic, indicating that the biomolecules in microalgae extracts have potential health benefits for human gut.
dc.language.iso	eng
dc.relation.ispartof	Food Chemistry, 2023, vol. 401, num. 134083
dc.subject	Algues
dc.subject	Antioxidants
dc.subject	Antiinflamatoris
dc.title	The impact of liquid-pressurized extracts of Spirulina, Chlorella and Phaedactylum tricornutum on in vitro antioxidant, antiinflammatory and bacterial growth effects and gut microbiota modulation
dc.type	journal article	es_ES
dc.date.updated	2022-11-28T14:19:16Z
dc.identifier.doi	10.1016/j.foodchem.2022.134083
dc.identifier.idgrec	155365
dc.rights.accessRights	open access	es_ES