NAGIOS: RODERIC FUNCIONANDO

Primary intraosseous squamous cell carcinoma arising from an odontogenic keratocyst:case series and literature review

Repositori DSpace/Manakin

IMPORTANT: Aquest repositori està en una versió antiga des del 3/12/2023. La nova instal.lació está en https://roderic.uv.es/

Primary intraosseous squamous cell carcinoma arising from an odontogenic keratocyst:case series and literature review

dc.contributor.author	Ye, Peng	es
dc.contributor.author	Wei, Tai	es
dc.contributor.author	Gao-, Yan-	es
dc.contributor.author	Zhang, Wen-Bo	es
dc.contributor.author	Peng, Xin	es
dc.date.accessioned	2023-06-16T08:36:36Z
dc.date.available	2023-06-16T08:36:36Z
dc.date.issued	2021	es
dc.identifier.citation	Ye, P., Wei, T., Gao, Y., Zhang, W., & Peng, X. (2021). Primary intraosseous squamous cell carcinoma arising from an odontogenic keratocyst: case series and literature review. En Medicina Oral Patología Oral y Cirugia Bucal (pp. e49-e55). Medicina Oral, S.L. https://doi.org/10.4317/medoral.23947	es
dc.identifier.uri	https://hdl.handle.net/10550/87992
dc.description.abstract	The aim of this study was to investigate the clinicopathologic features of primary intraosseous squamous cell carcinoma arising from an odontogenic keratocyst (PIOSCC ex OKC) and comprehensively improve the understanding of this disease. We retrospectively investigated five cases of PIOSCC ex OKC at Peking University School and Hospital of Stomatology. We also conducted a systematic review of studies on PIOSCC ex OKC by using online databases from their inception until February 2020. In our series of five cases, all lesions were located in the mandible. Three cases (60%) showed recurrent OKCs and two cases (40%) showed primary OKCs. During the follow-up period, one patient died of local relapse. No patients developed metastasis. On the basis of our literature survey, we selected 22 articles reporting 29 patients with PIOSCC ex OKC. Seven of these patients (24.1%) showed local recurrence, three patients (10.3%) developed cervical metastasis, three patients (10.3%) developed distant metastasis (in the pleura in one case and in the lung in two cases), and seven patients died from the disease during the follow-up period. The disease-specific 5-year survival rate in the study group was 53.2%. Through univariate and multivariate analysis, local recurrence was identified as the only significant independent prognostic factor for survival (P < 0.05). The results suggest that PIOSCC ex OKC is a rare intermediate-grade malignancy. Although elective neck dissection is typically unnecessary, adequate therapy should be applied to achieve the lowest local recurrence rate possible to ensure a favorable survival rate.	es
dc.subject	case control studies	es
dc.subject	head and neck cancer	es
dc.subject	pesticides	es
dc.subject	review	es
dc.subject	risk factors	es
dc.title	Primary intraosseous squamous cell carcinoma arising from an odontogenic keratocyst:case series and literature review	es
dc.type	journal article	es_ES
dc.subject.unesco	UNESCO:CIENCIAS MÉDICAS	es
dc.identifier.doi	10.4317/medoral.23947	es
dc.type.hasVersion	VoR	es_ES
dc.identifier.url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806341/