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Survival and prognostic factors in patients with oral squamous cell carcinoma

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Survival and prognostic factors in patients with oral squamous cell carcinoma

dc.contributor.author	Ferreira, Andressa Kelly Alves	es
dc.contributor.author	de Carvalho, Sérgio Henrique Gonçalves	es
dc.contributor.author	Granville-Garcia, Ana Flávia	es
dc.contributor.author	Sarmento, Dmitry José de Santana	es
dc.contributor.author	Agripino, Gustavo Gomes	es
dc.contributor.author	Guimaraes Abreu, Mauro Henrique Nogueira	es
dc.contributor.author	de Melo, Maria Cecília Freire	es
dc.contributor.author	Caldas-Júnior, Arnaldo-de-França	es
dc.contributor.author	Godoy, Gustavo-Pina	es
dc.date.accessioned	2023-06-16T08:36:40Z
dc.date.available	2023-06-16T08:36:40Z
dc.date.issued	2021	es
dc.identifier.citation	Ferreira, AK., Carvalho, SH., Granville-Garcia, AF., Sarmento, DJ., Agripino, GG., Abreu, MH., Melo, MC., Caldas Jr, Ad., & Godoy, GP. (2021). Survival and prognostic factors in patients with oral squamous cell carcinoma. En Medicina Oral Patología Oral y Cirugia Bucal (pp. e387-e392). Medicina Oral, S.L. https://doi.org/10.4317/medoral.24242	es
dc.identifier.uri	https://hdl.handle.net/10550/88036
dc.description.abstract	This study aimed to evaluate sociodemographic and clinical factors influencing overall survival (OS) in patients with oral squamous cell carcinoma (OSCC). Medical charts of 547 patients with OSCC from a public hospital in northeastern Brazil seen between 1999 and 2013 were evaluated. Survival analysis was performed using the Kaplan-Meier method. The influence of age, sex, ethnicity, clinical stage, anatomical location, type of treatment, and comorbidities on the patients? prognosis was evaluated. Cox proportional hazards regression model was used to identify independent prognostic factors. The 5-year OS was 39%. Multivariate analysis showed that age < 40 years (HR = 2.20; 95%CI: 1.02-4.72) and a single treatment modality (HR = 1.91; 95%CI: 1.37-2.67) were associated with a poor prognosis, while early clinical stage resulted in better outcomes (HR = 0.38; 95%CI: 0.25-0.58). OSCC patients in advanced clinical stages, diagnosed at a younger age, and submitted to a single therapeutic modality have a poorer prognosis.	es
dc.subject	head and neck neoplasms	es
dc.subject	neoplasms	es
dc.subject	glandular and epithelial	es
dc.subject	rare diseases	es
dc.subject	epidemiology	es
dc.subject	follow up studies	es
dc.title	Survival and prognostic factors in patients with oral squamous cell carcinoma	es
dc.type	journal article	es_ES
dc.subject.unesco	UNESCO:CIENCIAS MÉDICAS	es
dc.identifier.doi	10.4317/medoral.24242	es
dc.type.hasVersion	VoR	es_ES
dc.identifier.url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141315/