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Effect of antibiotic prophylaxis for preventing infectious complications following impacted mandibular third molar surgery. A randomized controlled trial

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Effect of antibiotic prophylaxis for preventing infectious complications following impacted mandibular third molar surgery. A randomized controlled trial

dc.contributor.author	Yanine, Nicolás	es
dc.contributor.author	Sabelle, Nicole	es
dc.contributor.author	Vergara-Gárate, Valentina	es
dc.contributor.author	Salazar, Josefina	es
dc.contributor.author	Araya, Ignacio	es
dc.contributor.author	Carrasco-Labra, Alonso	es
dc.contributor.author	Martín, Conchita	es
dc.contributor.author	Villanueva, Julio	es
dc.date.accessioned	2023-06-16T08:36:44Z
dc.date.available	2023-06-16T08:36:44Z
dc.date.issued	2021	es
dc.identifier.citation	Yanine, N., Sabelle, N., Vergara-Gárate, V., Salazar, J., Araya-Cabello, I., Carrasco-Labra, A., Martin, C., & Villanueva, J. (2021). Effect of antibiotic prophylaxis for preventing infectious complications following impacted mandibular third molar surgery. A randomized controlled trial. En Medicina Oral Patología Oral y Cirugia Bucal (pp. e703-e710). Medicina Oral, S.L. https://doi.org/10.4317/medoral.24274	es
dc.identifier.uri	https://hdl.handle.net/10550/88077
dc.description.abstract	The objective of this study was to determine the effect of antibiotic prophylaxis in preventing postoperative infections after extraction of impacted mandibular third molars. A Parallel-group, randomized, blind, placebo-controlled trial was performed. 154 patients were randomly allocated to 2 groups; experimental (n=77) receiving 2g amoxicillin 1 hour prior to surgery and control (n=77) receiving placebo. Primary outcome was postoperative infections and secondary outcome was the need for rescue analgesia. 4.5% of patients developed postoperative infections, five patients of the control group (4 alveolar osteitis, 1 surgical site infection) and two of the experimental group (1 alveolar osteitis, 1 surgical site infection). Difference between groups was not statistically significant, RR=0.4 (95%CI 0.08-1.99, ?=0.41) NNTB=26. Rescue analgesia intake was significantly higher in the control group (41 vs 18 patients of experimental group) RR=0.49 (95%CI 0.32-0.75, ?<0.05) NNTB=3. The use of 2g amoxicillin 1 hour before surgery was not effective in significantly reducing the risk of postoperative infections from impacted mandibular third molars extraction, when compared to placebo. Nevertheless, antibiotic prophylaxis was associated with a reduced need for rescue analgesia.	es
dc.subject	periapical radiography	es
dc.subject	panoramic radiography	es
dc.subject	cbct	es
dc.subject	sensitivity	es
dc.subject	treatment outcome	es
dc.subject	size of periapical radiolucency	es
dc.subject	area	es
dc.subject	volume	es
dc.title	Effect of antibiotic prophylaxis for preventing infectious complications following impacted mandibular third molar surgery. A randomized controlled trial	es
dc.type	journal article	es_ES
dc.subject.unesco	UNESCO:CIENCIAS MÉDICAS	es
dc.identifier.doi	10.4317/medoral.24274	es
dc.type.hasVersion	VoR	es_ES
dc.identifier.url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601648/