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Efficacy of non-surgical periodontal treatment on patients with coronary artery disease:a meta-analysis of randomized controlled trials

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Efficacy of non-surgical periodontal treatment on patients with coronary artery disease:a meta-analysis of randomized controlled trials

dc.contributor.author	Liu, Chundi	es
dc.contributor.author	Shi, Feifei	es
dc.contributor.author	Li, Wenjie	es
dc.contributor.author	Chen, Jun	es
dc.date.accessioned	2023-06-16T08:36:52Z
dc.date.available	2023-06-16T08:36:52Z
dc.date.issued	2022	es
dc.identifier.citation	Liu, C., Shi, F., Li, W., & Chen, J. (2022). Efficacy of non-surgical periodontal treatment on patients with coronary artery disease: a meta-analysis of randomized controlled trials. En Medicina Oral Patología Oral y Cirugia Bucal (pp. e578-e587). Medicina Oral, S.L. https://doi.org/10.4317/medoral.25514	es
dc.identifier.uri	https://hdl.handle.net/10550/88164
dc.description.abstract	Coronary artery disease (CAD) is defined as one of the most common cardiovascular diseases (CVDs). Periodontitis is one of the risk factors for CAD. PubMed, Embase and Cochrane Library databases were carefully and thoroughly retrieved until October 2021. On the basis of the inclusion and exclusion criteria, eligible articles were selected strictly to identify randomized controlled trials (RCTs). Using Cochran's Q statistic, Review Manager 5.4 and Stata 16, data were extracted, and a comprehensive analysis was carried out. Six RCTs of 619 patients were included in this study, including 360 in the intervention group (IG) and 259 in the control group (CG). Meta-analysis showed significant difference for C-reactive protein (CRP) (1.20mg/L, 95% CI: 1.13 to 1.27, p < 0.00001) after non-surgical periodontal therapy (NSPT), but showed no significant difference for interleukin-6 (IL-6) (1.19mg/L, 95% CI: -1.03 to 3.40, p=0.29), flow-mediated dilation (FMD) (-1.64%, 95% CI: -4.95 to 1.67, p=0.33), triacylglycerol (TG) (-0.02mg/dL, 95% CI: -0.31 to 0.27, p=0.90), total cholesterol (TC) (0.04mg/dL, 95% CI: -0.25 to 0.33, p=0.90), low-density lipoprotein cholesterol (LDL-C) (0.00mg/dL, 95% CI: -0.29 to 0.29, p=0.99) and high-density lipoprotein cholesterol (HDL-C) (0.11mg/dL, 95% CI: -0.18 to 0.40, p=0.46). The impact of NSPT on the reduction of CRP in patients of CAD with periodontitis is significant. NSPT can be considered as an important preventive strategy for major cardiovascular events in CAD.	es
dc.subject	inflammatory bowel disease	es
dc.subject	crohn's disease	es
dc.subject	ulcerative colitis	es
dc.subject	undetermined	es
dc.subject	systemic extraintestinal manifestations	es
dc.subject	aphthous stomatitis	es
dc.title	Efficacy of non-surgical periodontal treatment on patients with coronary artery disease:a meta-analysis of randomized controlled trials	es
dc.type	journal article	es_ES
dc.subject.unesco	UNESCO:CIENCIAS MÉDICAS	es
dc.identifier.doi	10.4317/medoral.25514	es
dc.type.hasVersion	VoR	es_ES
dc.identifier.url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648645/