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The relative importance of transcription rate, cryptic transcription and mRNA stability on shaping stress responses in yeast

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The relative importance of transcription rate, cryptic transcription and mRNA stability on shaping stress responses in yeast

dc.contributor.author	García Martínez, José
dc.contributor.author	Ayala Gallego, Guillermo
dc.contributor.author	Pelechano García, Vicente José
dc.contributor.author	Chávez, Sebastián
dc.contributor.author	Herrero, Enrique
dc.contributor.author	Pérez Ortín, José Enrique
dc.date.accessioned	2013-12-04T11:18:59Z
dc.date.available	2013-12-04T11:18:59Z
dc.date.issued	2012
dc.identifier.citation	García Martínez, José Ayala Gallego, Guillermo Pelechano García, Vicente José Chávez, S. Herrero, E. Pérez Ortín, José Enrique 2012 The relative importance of transcription rate, cryptic transcription and mRNA stability on shaping stress responses in yeast Transcription 3 1 39 44
dc.identifier.uri	http://hdl.handle.net/10550/31722
dc.description.abstract	It has been recently stated that stress-responding genes in yeast are enriched in cryptic transcripts and that this is the cause of the differences observed between mRNA amount and RNA polymerase occupancy profiles. Other studies have shown that such differences are mainly due to modulation of mRNA stabilities. Here we analyze the relationship between the presence of cryptic transcripts in genes and their stress response profiles. Despite some of the stress-responding gene groups being indeed enriched in specific classes of cryptic transcripts, we found no statistically significant evidence that cryptic transcription is responsible for the differences observed between mRNA and transcription rate profiles.
dc.relation.ispartof	Transcription, 2012, vol. 3, num. 1, p. 39-44
dc.subject	Genètica molecular
dc.subject	RNA
dc.subject	Saccharomyces
dc.subject	Transcripció genètica
dc.title	The relative importance of transcription rate, cryptic transcription and mRNA stability on shaping stress responses in yeast
dc.type	journal article	es_ES
dc.date.updated	2013-12-04T11:18:59Z
dc.identifier.doi	10.4161/trns.3.1.19416
dc.identifier.idgrec	081459
dc.rights.accessRights	open access	es_ES
dc.identifier.url	10.4161/trns.3.1.19416