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Mortality associated with the use of inappropiate drugs according Beers Criteria: a systematic review

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Mortality associated with the use of inappropiate drugs according Beers Criteria: a systematic review

dc.contributor.author	Sichieri, Karina
dc.contributor.author	Baldacin, Adriano
dc.contributor.author	Takahashi, Juliana
dc.contributor.author	Secoli, Silvia
dc.contributor.author	Cuce, Moacyr
dc.contributor.author	Martinez, Monica
dc.contributor.author	Fernández Garrido, Julio Jorge
dc.date.accessioned	2014-04-10T18:07:26Z
dc.date.available	2014-04-10T18:07:26Z
dc.date.issued	2013
dc.identifier.citation	Sichieri, Karina Baldacin, Adriano Takahashi, Juliana Secoli, Silvia Cuce, Moacyr Martinez, Monica Fernández Garrido, Julio Jorge 2013 Mortality associated with the use of inappropiate drugs according Beers Criteria: a systematic review Advances in Pharmacology and Pharmacy 1 2 74 84
dc.identifier.uri	http://hdl.handle.net/10550/34539
dc.description.abstract	The aims of this systematic review are to identify and analyse the scientist literature available evidence about the use of potentially inappropriate medications, according to the Beers Criteria, that is associated with mortality in the elderly people.It have been made a search of publications in most traditional electronic databases among the scientific community (Pubmed / Medline, EMBASE and Web of Science) and it have been selected publications that obey the criteria of 'observational study', 'elderly' and 'Beers Criteria' and that they had as a result the mortality of the study population .After publications selection it proceeded to dump data by two researchers independently to avoid selection bias. The methodological quality of the selected studies was assessed by the checklist Newcastle-Ottawa. The final sample of this systematic review has been made up of 17 studies published in Pubmed and Embase databases majority, 8 of which make up the meta-analysis. In descriptive synthesis has been observed that most of the studies have a level of evidence IV (94'1%) with cohortdelineation (94'1%) and non-probability sampling technique (70'6%).Data collection was prospective in 58'8% of cases, with a sample (n) greater than 1000 elderly (64'7%) and followed up for 6 to 12 months (52'9%).The meta-analysis involving 90.611 elders informed that users who take inappropriate drug according to the Beers Criteria had a higher relative risk for mortality outcome (RR = 1.11, 95% CI 1'01-1'22 P = 0'023), regardless of study stage, comorbidity presence, polypharmacy or type of inappropriate medication used.
dc.relation.ispartof	Advances in Pharmacology and Pharmacy, 2013, vol. 1, num. 2, p. 74-84
dc.subject	Infermeria
dc.subject	Farmacologia
dc.title	Mortality associated with the use of inappropiate drugs according Beers Criteria: a systematic review
dc.type	journal article	es_ES
dc.date.updated	2014-04-10T18:07:27Z
dc.identifier.doi	10.13189/app.2013.010205
dc.identifier.idgrec	095009
dc.rights.accessRights	open access	es_ES
dc.identifier.url	10.13189/app.2013.010205