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Xeroderma Pigmentosum: a case report with oral implications

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Xeroderma Pigmentosum: a case report with oral implications

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dc.contributor.author Lopes Cardoso, Camila es
dc.contributor.author Ramos Fernandes, Luciana Maria es
dc.contributor.author Ferreira Rocha, Julierme es
dc.contributor.author Teixeira Soares, Cleverson es
dc.contributor.author Antônio Barreto, Jaison es
dc.contributor.author Humberto Damante, José es
dc.date.accessioned 2014-05-21T12:44:52Z
dc.date.available 2014-05-21T12:44:52Z
dc.date.issued 2012 es
dc.identifier.citation Lopes Cardoso, Camila ; Ramos Fernandes, Luciana Maria ; Ferreira Rocha, Julierme ; Teixeira Soares, Cleverson ; Antônio Barreto, Jaison ; Humberto Damante, José. Xeroderma Pigmentosum: a case report with oral implications. En: Journal of Clinical and Experimental Dentistry, 2012, Vol. 4, No. 4: 248-251 es
dc.identifier.uri http://hdl.handle.net/10550/35277
dc.description.abstract Xeroderma Pigmentosum is a rare autosomal recessive genetic disorder characterized by defective DNA repair leading to clinical and cellular hypersensitivity to ultraviolet radiation and carcinogenic agents. Important clinical features are: intense cutaneous photosensitivity, xerosis, poikiloderma, actinic keratosis, acute burning under minimal sun exposure, erythemas, hyperpigmented lentiginous macules, and malignant lesions in sun-exposed areas, including basocellular carcinoma, squamous cell carcinoma, and melanoma. There is a great involvement of many parts of the body, especially head and neck. The oral manifestations are mainly related to the occurrence of malignant tumors in the lips, tongue and buccal mucosa. This paper reports a rare case of Xeroderma Pigmentosum in a 41-year-old male presenting mainly dermatological, neurological and ophthalmological involvement. Oral implications such as severe oral pain and mouth opening limitation were present due to perioral scars. In addition, this paper discuss some important aspects concerning the role of the dental professional management of this entity, since XP patients require constant dental care and follow-up in order to control the occurrence of new lesions on the lips or inside oral cavity. en_US
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Xeroderma Pigmentosum: a case report with oral implications es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.type.hasVersion VoR es_ES

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