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Oral squamous cell carcinoma among Yemenis: onset in young age and presentation at advanced stage

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Oral squamous cell carcinoma among Yemenis: onset in young age and presentation at advanced stage

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dc.contributor.author Halboub, Esam es
dc.contributor.author Al-Mohaya, Maha es
dc.contributor.author Abdulhuq, Mahmoud es
dc.contributor.author Al-Mandili, Ahmad es
dc.contributor.author Al-Anazi, Yousef es
dc.date.accessioned 2014-05-21T12:44:53Z
dc.date.available 2014-05-21T12:44:53Z
dc.date.issued 2012 es
dc.identifier.citation Halboub, Esam ; Al-Mohaya, Maha ; Abdulhuq, Mahmoud ; Al-Mandili, Ahmad ; Al-Anazi, Yousef. Oral squamous cell carcinoma among Yemenis: onset in young age and presentation at advanced stage. En: Journal of Clinical and Experimental Dentistry, 2012, Vol. 4, No. 4: 221-225 es
dc.identifier.uri http://hdl.handle.net/10550/35279
dc.description.abstract Objectives: Oral cancer represents a health burden worldwide. Up to 90% of oral cancer cases are squamous cell carcinomas (SCC). The data on oral SCC in Yemen are lacking. The objective of this study therefore was to describe and analyze the demographic, clinical and histological characteristics of Yemeni patients with oral SCC. Study design: In this cross-sectional study, two sets of retrospective data for Yemeni cancer patients were obtained officially by two different registries. Patients with oral SCC were included. Their ages were dichotomized using 40 and 45 years alternately as individual cut-points for young and old patients. The patients` demographic, clinical and histological characteristics were statistically analyzed. Results: There were 457 Yemenis with oral SCC; 253 patients (55.4%) were men. The overall mean age was 58.15'}14.11 years. The tongue was the most affected oral sub-site accounting for 53% of the reported cases. The well and moderately differentiated oral SCC accounted for 55.5% and 25.6% of the total cases respectively. Noteworthy, 62 patients (14%) were affected by the age of .40; this increased to 105 patients (23%) aged .45 years. Additionally, a high proportion of oral SCC patients (62%, 283) were diagnosed at advanced tumor stages (regional extension or metastasized). The distributions of histological grades and tumor stages in young and old patients were significantly different (P=0.006 and 0.026 respectively). Conclusion: The relative frequency of oral SCC among Yemeni young people is high. Unfortunately, most of oral SCC patients in Yemen were diagnosed at advanced stage. en_US
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Oral squamous cell carcinoma among Yemenis: onset in young age and presentation at advanced stage es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.type.hasVersion VoR es_ES

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