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Usefulness of salivary alpha amylase as a biomarker of chronic stress and stress related oral mucosal changes ' a pilot study

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Usefulness of salivary alpha amylase as a biomarker of chronic stress and stress related oral mucosal changes ' a pilot study

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dc.contributor.author Vineetha, Ravindranath es
dc.contributor.author Pai, Keerthilatha M. es
dc.contributor.author Vengal, Manoj es
dc.contributor.author Gopalakrishna, Kodyalamoole es
dc.contributor.author Narayanakurup, Dinesh es
dc.date.accessioned 2014-05-22T10:06:46Z
dc.date.available 2014-05-22T10:06:46Z
dc.date.issued 2014 es
dc.identifier.citation Vineetha, Ravindranath ; Pai, Keerthilatha M. ; Vengal, Manoj ; Gopalakrishna, Kodyalamoole ; Narayanakurup, Dinesh. Usefulness of salivary alpha amylase as a biomarker of chronic stress and stress related oral mucosal changes ' a pilot study. En: Journal of Clinical and Experimental Dentistry, 2014, Vol. 6, No. 2: 132-137 es
dc.identifier.uri http://hdl.handle.net/10550/35392
dc.description.abstract Introduction: Salivary biomarkers are suggested to provide a reliable, noninvasive and objective measurement of chronic psychosocial stress and helps in assessment of pivotal role of stress in causation or precipitation of multitude of health problems Objectives: To evaluate the usefulness of salivary alpha amylase activity as an objective indicator of chronic stress and to find out any correlation between stress- related mucosal complaints and its levels. Study Design: Study was conducted among 50 subjects suffering from chronic stress related problems and 50 nonstressed individuals who were screened with a psychometric questionnaire. Brief case history and oral examination was carried out and about one ml of unstimulated saliva was collected. Salivary alpha amylase levels estimated were compared between study and control group and between subjects with and without oral mucosal changes using non parametric Mann Whitney U test Results: There was statistically significant higher salivary alpha amylase levels in study group (p = .002) and salivary alpha amylase between the oral mucosal complaints group and without oral mucosal complaints group within the total study population were found to be statistically significant (p=0.045). Conclusion: Salivary amylase activity increases in patients with chronic psychosocial stress and may be used as a biomarker of chronic stress, but it may not be an indicator to suggest the development of stress related oral mucosal changes. en_US
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Usefulness of salivary alpha amylase as a biomarker of chronic stress and stress related oral mucosal changes ' a pilot study es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.type.hasVersion VoR es_ES

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