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Cytological changes in the oral mucosa after use of a mouth rinse with alcohol: a prospective double blind control study

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Cytological changes in the oral mucosa after use of a mouth rinse with alcohol: a prospective double blind control study

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dc.contributor.author Bagán Sebastián, José Vicente es
dc.contributor.author Vera Sempere, Francisco José es
dc.contributor.author Marzal Gamarra, Cristina es
dc.contributor.author Pellín Carcelén, Ana es
dc.contributor.author Martí Bonmatí, Ezequiel es
dc.contributor.author Bagán Debón, Leticia es
dc.date.accessioned 2014-05-28T12:42:55Z
dc.date.available 2014-05-28T12:42:55Z
dc.date.issued 2012 es
dc.identifier.citation Bagán Sebastián, José Vicente ; Vera Sempere, Francisco José ; Marzal Gamarra, Cristina ; Pellín Carcelén, Ana ; Martí Bonmatí, Ezequiel ; Bagan Debon, Leticia Maria. Cytological changes in the oral mucosa after use of a mouth rinse with alcohol: a prospective double blind control study. En: Medicina oral, patología oral y cirugía bucal. Ed inglesa, 2012, Vol. 17, No. 6: 956-961 es
dc.identifier.uri http://hdl.handle.net/10550/35536
dc.description.abstract Aim: The aim of this preliminary study was to detect cytological changes in the oral mucosa after using a mouth wash with alcohol. Material and Methods: A prospective double-blind, controlled study was performed, for 6 months. Group 1 consisted of 30 subjects who used a mouth rinse with 26.9% of alcohol [Listerine ® ] and Group 2 consisted of 30 subjects who used a mouth rinse with the same ingredients but with no alcohol. We obtained three cytological samples from the oral mucosa. The presence of cytological atypia, binucleation and karyorrhesis, and type of cells were studied. We also used a fluorescent in situ hybridization technique (FISH) in 15 samples in each group, for the micronucleus. Results: We found no clinical mucosal alteration after using the mouth wash at the end of the study in either group. We observed no cytological differences between the groups at the end of the study (p>0.05). Regarding the study of the micronucleus by FISH, we observed no significant difference between the groups (p>0.05). Conclusions: Our results showed no cytological alteration in patients using a mouth rinse with alcohol, but these findings should be considered preliminary results, to be confirmed in a greater sample of patients. en_US
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Cytological changes in the oral mucosa after use of a mouth rinse with alcohol: a prospective double blind control study es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.type.hasVersion VoR es_ES

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