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Mesenchymal dental stem cells in regenerative dentistry

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Mesenchymal dental stem cells in regenerative dentistry

dc.contributor.author	Rodríguez Lozano, Francisco Javier	es
dc.contributor.author	Insausti, Carmen Luisa	es
dc.contributor.author	Iniesta, Francisca	es
dc.contributor.author	Blanquer, Miguel	es
dc.contributor.author	Ramírez, María del Carmen	es
dc.contributor.author	Meseguer, Luis	es
dc.contributor.author	Meseguer Henarejos, Ana Belén	es
dc.contributor.author	Marín Atucha, Noemi Teresa	es
dc.contributor.author	Martínez, Salvador	es
dc.contributor.author	Moraleda Jiménez, José María	es
dc.date.accessioned	2014-05-28T12:42:57Z
dc.date.available	2014-05-28T12:42:57Z
dc.date.issued	2012	es
dc.identifier.citation	Rodríguez Lozano, Francisco Javier ; Insausti, Carmen Luisa ; Iniesta, Francisca ; Blanquer, Miguel ; Ramírez, María del Carmen ; Meseguer, Luis ; Meseguer Henarejos, Ana Belén ; Marín Atucha, Noemi Teresa ; Martínez, Salvador ; Moraleda Jiménez, José María. Mesenchymal dental stem cells in regenerative dentistry. En: Medicina oral, patología oral y cirugía bucal. Ed inglesa, 2012, Vol. 17, No. 6: 1062-1067	es
dc.identifier.uri	http://hdl.handle.net/10550/35542
dc.description.abstract	In the last decade, tissue engineering is a field that has been suffering an enormous expansion in the regenerative medicine and dentistry. The use of cells as mesenchymal dental stem cells of easy access for dentist and oral surgeon, immunosuppressive properties, high proliferation and capacity to differentiate into odontoblasts, cementoblasts, osteoblasts and other cells implicated in the teeth, suppose a good perspective of future in the clinical dentistry. However, is necessary advance in the known of growth factors and signalling molecules implicated in tooth development and regeneration of different structures of teeth. Furthermore, these cells need a fabulous scaffold that facility their integration, differentiation, matrix synthesis and promote multiple specific interactions between cells. In this review, we give a brief description of tooth development and anatomy, definition and classification of stem cells, with special attention of mesenchymal stem cells, commonly used in the cellular therapy for their trasdifferentiation ability, non ethical problems and acceptable results in preliminary clinical trials. In terms of tissue engineering, we provide an overview of different types of mesenchymal stem cells that have been isolated from teeth, including dental pulp stem cells (DPSCs), stem cells from human exfoliated deciduous teeth (SHEDs), periodontal ligament stem cells (PDLSCs), dental follicle progenitor stem cells (DFPCs), and stem cells from apical papilla (SCAPs), growth factors implicated in regeneration teeth and types of scaffolds for dental tissue regeneration.	en_US
dc.subject	Odontología	es
dc.subject	Ciencias de la salud	es
dc.title	Mesenchymal dental stem cells in regenerative dentistry	es
dc.type	journal article	es_ES
dc.subject.unesco	UNESCO::CIENCIAS MÉDICAS	es
dc.type.hasVersion	VoR	es_ES