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The relevance of uniform reporting in oral leukoplakia: definition, certainty factor and staging based on experience with 275 patients

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The relevance of uniform reporting in oral leukoplakia: definition, certainty factor and staging based on experience with 275 patients

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dc.contributor.author Brouns, Elisabeth-REA es
dc.contributor.author Baart, Jacques A es
dc.contributor.author Bloemena, Elisabeth es
dc.contributor.author Karagozoglu, Hakki es
dc.contributor.author Van der Waal, Isaäc es
dc.date.accessioned 2014-05-28T12:44:45Z
dc.date.available 2014-05-28T12:44:45Z
dc.date.issued 2013 es
dc.identifier.citation Brouns, Elisabeth-REA ; Baart, Jacques A ; Bloemena, Elisabeth ; Karagozoglu, Hakki ; Van der Waal, Isaäc. The relevance of uniform reporting in oral leukoplakia: definition, certainty factor and staging based on experience with 275 patients. En: Medicina oral, patología oral y cirugía bucal. Ed inglesa, 2013, Vol. 18, No. 1: 19-26 es
dc.identifier.uri http://hdl.handle.net/10550/35550
dc.description.abstract The aim of the present study was to evaluate the definition of oral leukoplakia, proposed by the WHO in 2005 and taking into account a previously reported classification and staging system, including the use of a Certainty factor of four levels with which the diagnosis of leukoplakia can be established. In the period 1997-2012 a hospital-based population of 275 consecutive patients with a provisional diagnosis of oral leukoplakia has been examined. In only 176 patients of these 275 patients a firm diagnosis of leukoplakia has been established based on strict clinicopathological criteria. The 176 patients have subsequently been staged using a classification and staging system based on size and histopathologic features. For use in epidemiological studies it seems acceptable to accept a diagnosis of leukoplakia based on a single oral examination (Certainty level 1). For studies on management and malignant transformation rate the recommendation is made to include the requirement of histopathologic examination of an incisional or excisional biopsy, representing Certainty level 3 and 4, respectively. This recommendation results in the following definition of oral leukoplakia: 'A predominantly white lesion or plaque of questionable behaviour having excluded, clinically and histopathologically, any other definable white disease or disorder'. Furthermore, we recommend the use of strict diagnostic criteria for predominantly white lesions for which a causative factor has been identified, e.g. smokers' lesion, frictional lesion and dental restoration associated lesion. en_US
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title The relevance of uniform reporting in oral leukoplakia: definition, certainty factor and staging based on experience with 275 patients es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.type.hasVersion VoR es_ES

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