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Immunomodulatory drugs: oral and systemic adverse effects

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Immunomodulatory drugs: oral and systemic adverse effects

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dc.contributor.author Bascones Martínez, Antonio es
dc.contributor.author Mattila, Riikka es
dc.contributor.author Gómez Font, Rafael es
dc.contributor.author Meurman, Jukka H. es
dc.date.accessioned 2014-07-04T07:53:31Z
dc.date.available 2014-07-04T07:53:31Z
dc.date.issued 2014 es
dc.identifier.citation Bascones Martínez, Antonio ; Mattila, Riikka ; Gómez Font, Rafael ; Meurman, Jukka H.. Immunomodulatory drugs: oral and systemic adverse effects. En: Medicina oral, patología oral y cirugía bucal. Ed inglesa, 2014, Vol. 19, No. 1: 24-31 es
dc.identifier.uri http://hdl.handle.net/10550/36851
dc.description.abstract Objectives: The main objectives are to present the different adverses effects of the immunomodulatory drugs that can impair the quality of life of the immunosupressed patients and study the impact of immunomodualtion on oral diseases. Immunomodulatory drugs have changed the treatment protocols of many diseases where immune functions play a central role, such as rheumatic diseases. Their effect on oral health has not been systematically investigated, however. Study Design: We review current data on the new immunomodulatory drugs from the oral health perspective based on open literature search of the topic. Results: These target specific drugs appear to have less drug interactions than earlier immunomodulating medicines but have nevertheless potential side effects such as activating latent infections. There are some data showing that the new immunomodulatory drugs may also have a role in the treatment of certain oral diseases such as lichen planus or ameliorating symptoms in Sjögren´s syndrome, but the results have not been overly promising. Conclusions: In general, data are sparse of the effect of these new drugs vs. oral diseases and there are no properly powered randomized controlled trials published on this topic. en_US
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Immunomodulatory drugs: oral and systemic adverse effects es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.type.hasVersion VoR es_ES
dc.identifier.url http://www.medicinaoral.com/pubmed/medoralv19_i1_p24.pdf es

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