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Burkitt's lymphoma of the jaws in the Amazon region of Brazil

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Burkitt's lymphoma of the jaws in the Amazon region of Brazil

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dc.contributor.author Rebelo-Pontes, Hélder-Antônio es
dc.contributor.author Abreu, Michelle-Carvalho de es
dc.contributor.author Guimarães, Douglas-Magno es
dc.contributor.author Paiva Fonseca, Felipe es
dc.contributor.author Andrade, Bruno Augusto Benevenuto de es
dc.contributor.author Almeida, Oslei Paes de es
dc.contributor.author Júnior, Décio-dos-Santos-Pinto es
dc.contributor.author Corrêa-Pontes, Flávia-Sirotheau es
dc.date.accessioned 2014-07-04T07:53:30Z
dc.date.available 2014-07-04T07:53:30Z
dc.date.issued 2014 es
dc.identifier.citation Rebelo-Pontes, Hélder-Antônio ; Abreu, Michelle-Carvalho de ; Guimarães, Douglas-Magno ; Paiva Fonseca, Felipe ; Andrade, Bruno Augusto Benevenuto de ; Almeida, Oslei Paes de ; Júnior, Décio-dos-Santos-Pinto ; Corrêa-Pontes, Flávia-Sirotheau. Burkitt's lymphoma of the jaws in the Amazon region of Brazil. En: Medicina oral, patología oral y cirugía bucal. Ed inglesa, 2014, Vol. 19, No. 1: 32-37 es
dc.identifier.uri http://hdl.handle.net/10550/36855
dc.description.abstract Objectives: To describe the clinicopathologic and immunohistochemical features of Burkitt's lymphoma of the jaws in 7 patients of Northern Brazil. Study Design: Clinical data concerning gender, age, affected site, clinical presentation, symptomatology and follow-up were collected from the clinical files. Histopathology was complemented with a broad immunohistochemical panel and in situ hybridization for Epstein-Barr virus (EBV). Results: Most of the patients were infants and 5 out of 7 were males. The mandible was affected in 5 cases and all patients also presented abdominal involvement. All cases were positive for CD45, CD20, CD79a, CD10, Bcl-6 and EBV. Ki-67 proliferative index was approximately 100%. Six patients were treated with R-CHOP (Rituximab + Cyclophosphamide, Doxorubicin, Vincristine and Prednisolone) chemotherapy, and 2 of these died of the disease. One young adult patient refused treatment and died 3 months after initial diagnosis. Conclusions: Burkitt's lymphoma of the jaws diagnosed in the Amazon region of Brazil present similar clinicopathologic features to those described in endemic areas of Africa, including EBV positivity. en_US
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Burkitt's lymphoma of the jaws in the Amazon region of Brazil es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.type.hasVersion VoR es_ES
dc.identifier.url http://www.medicinaoral.com/pubmed/medoralv19_i1_p32.pdf es

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