What can we predict for 2020? Solar and lunar eclipses? Without a doubt. Climate change? Most likely. Rising sea levels? Signs point to yes. Beyond that, however, in the world of human events, it is best to be cautious. In the field of health and medicine (or anywhere else, for that matter), no one predicted the most important discoveries of the twentieth century. Economists were no more successful in foreseeing financial or economic crises. The pundits did not forecast any of the recent wars, disruptions or even the recent Arab Spring movements indeed, political experts turned out to be only slightly more accurate than dart-throwing chimpanzees in divining what was in store for the future.1 As the World Health Organization (WHO) and the wider scientific community looked to East Asia in anticipation of the next outbreak of H5N1, the influenza H1N1 pandemic took hold in Mexico. Tsunamis, volcanic eruptions, earthquakes, drug scandals, outbreaks of emerging diseases and political disruptions are notoriously unpredictable, as Nassim Nicholas Taleb brilliantly highlighted in his book The Black Swan.