Parotid gland solitary fibrous tumor with mandibular bone destruction and aggressive behavior
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Alonso Rodríguez, Estefanía; González Otero, Teresa; Castro Calvo, A.; Ruiz Bravo, Elena
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Aquest document és un/a article, creat/da en: 2014
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Introduction: Solitary fibrous tumor is associated with serosal surfaces. Location in the salivary glands is extremely
unusual. Extrathoracic tumors have an excellent prognosis associated with their benign clinical behavior. We report
an aggressive and recurrent case of this tumor. We review the clinical presentation, inmunohistochemical profiles
and therapeutic approaches.
Case Report: A 73-years-old woman presented a mass in her right parotid gland. She had a past history of right
superficial parotidectomy due to a neurilemoma. FNAB and magnetic resonance were non-specific. After a tumor
resection, microscopic findings were spindled tumor cells with reactivity to CD34, bcl-2 and CD99 and the tumor
was diagnosed as Solitary Fibrous Tumor. The patient suffered two recurrences and the tumor had a histological
aggressive behavior and a destruction of the cortical bone of the mandible adjacent to the mass. A marginal mandi
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bulectomy with an alveolar inferior nerve lateralization was performed.
Conclusions: Solitary fibrous tumor is a very rare tumor. Usually, they are benign, but occasionally they can be
aggressive. Complete resection is the most important prognostic factor and no evidence supports the efficacy of any
therapy different to surgery. Due to the unknown prognosis and to the small number of cases reported, a long-term
follow-up is guaranteed.
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