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Stress and memory performance in older men and women: The role of the Hypothalamus-Pituitary-Adrenal axis

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Stress and memory performance in older men and women: The role of the Hypothalamus-Pituitary-Adrenal axis

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dc.contributor.advisor Salvador Fernández-Montejo, Alicia
dc.contributor.author Almela Zamorano, Mercedes
dc.contributor.other Departament de Psicobiologia es_ES
dc.date.accessioned 2014-09-19T08:54:49Z
dc.date.available 2014-09-20T06:10:04Z
dc.date.issued 2011
dc.identifier.uri http://hdl.handle.net/10550/38919
dc.description.abstract When we refer to the HPA-axis, we are referring to a complex communication system that encompasses three different regions of our body. This communication system is crucial for our survival, because it is an important part of our defense when faced with threats, and because it coordinates the re-establishment of homeostasis when the threat is over. Therefore, the activity of the HPA-axis is a part of the stressresponse, and its main function is to improve our chances of survival in the presence of threats to our physical or psychological well-being. Communication is established between the hypothalamus, the pituitary gland and the adrenal gland through the release of hormones (see figure 1). When the HPAaxis is activated due to, for example, the presence of a physical or psychological stressor, the paraventricular nucleus of the hypothalamus releases corticotropin releasing hormone (CRH) and arginine-vasopressin (AVP) into the portal circulation of the median eminence. CRH and AVP induce the pituitary gland to secrete adrenocorticotropic hormone (ACTH) into the bloodstream, which stimulates the cortex of the adrenal glands, where, finally, glucocorticoids are released into the bloodstream (Ulrich- Lai and Herman, 2009). The most notable glucocorticoid in humans is cortisol. es_ES
dc.format.extent 190 p. es_ES
dc.language.iso en es_ES
dc.title Stress and memory performance in older men and women: The role of the Hypothalamus-Pituitary-Adrenal axis es_ES
dc.type doctoral thesis es_ES
dc.subject.unesco UNESCO::PSICOLOGÍA es_ES
dc.embargo.terms 0 days es_ES

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