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Verrucous carcinoma of the oral mucosa: an epidemiological and follow-up study of patients treated with surgery in 5 last years

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Verrucous carcinoma of the oral mucosa: an epidemiological and follow-up study of patients treated with surgery in 5 last years

dc.contributor.author	Candau Álvarez, Alberto	es
dc.contributor.author	Dean Ferrer, Alicia	es
dc.contributor.author	Alamillos Granados, Francisco	es
dc.contributor.author	Heredero Jung, Susana	es
dc.contributor.author	García García, Blas	es
dc.contributor.author	Ruiz Masera, J.J.	es
dc.contributor.author	Arévalo Arévalo, Rafael	es
dc.contributor.author	Zafra Camacho, F.	es
dc.contributor.author	Valenzuela Salas, B.	es
dc.date.accessioned	2015-01-08T12:34:04Z
dc.date.available	2015-01-08T12:34:04Z
dc.date.issued	2014	es
dc.identifier.citation	Candau Álvarez, Alberto ; Dean Ferrer, Alicia ; Alamillos Granados, Francisco ; Heredero Jung, Susana ; García García, Blas ; Ruiz Masera, J.J. ; Arévalo Arévalo, Rafael ; Zafra Camacho, F. ; Valenzuela Salas, B.. Verrucous carcinoma of the oral mucosa: an epidemiological and follow-up study of patients treated with surgery in 5 last years. En: Medicina oral, patología oral y cirugía bucal. Ed inglesa, 2014, Vol. 19, No. 5: 506-511	es
dc.identifier.uri	http://hdl.handle.net/10550/41143
dc.description.abstract	Introduction: Oral Verrucous Carcinoma (OVC) is described apart of the Squamous Cell Carcinoma (SCC) due to its specific properties. The objective of our study is to show our series of cases of OVC and to compare with the SCC in terms of clinical manifestations, epidemiology, histopathology, treatment and follow-up. Material and Methods: This is a retrospective study of all the OVC treated in our department between January- 2007 and December-2011. The analyzed variables were sex, age, localization in the oral cavity, histopathology, number of biopsies needed to diagnose OVC, TNM classification, treatment and recurrences during follow-up. Results: Our sample was composed by n=14 patients, 57% female, with a mean age of 69.14 years. The most com - mon localization was buccal mucosa (n=5). Seven patients were diagnosed of OVC with the first biopsy. TNM classification was: pT1: 7 patients, pT2: 3 patients, pT3: 3 patients, pT4: 1 patient. No cervical metastases were observed either in cervical neck dissection or during the follow-up of the patients. The treatment was surgery with clinical resection margins up to 1 cm in all cases, followed by radiotherapy in selected cases. Only n=1 patient (7.69%) presented a recurrence after 34 months of follow-up. The overall survival rate was 92.85%. Conclusions: In our population, OVC represents the 6.16% of all oral cavity and oropharynx cancer, and is more frequent in female patients above 70 years old. It uses to rise over a previous lesion, and usually affects the buccal mucosa. In patients with high suspicious lesions, more than one biopsy may be needed to diagnose OVC. No pa - tient showed cervical dissemination. In our experience, treatment based on local resection, without cervical neck dissection, could be a good option for these patients.	en_US
dc.subject	Odontología	es
dc.subject	Ciencias de la salud	es
dc.title	Verrucous carcinoma of the oral mucosa: an epidemiological and follow-up study of patients treated with surgery in 5 last years	es
dc.type	journal article	es_ES
dc.subject.unesco	UNESCO::CIENCIAS MÉDICAS	es
dc.type.hasVersion	VoR	es_ES
dc.identifier.url	http://www.medicinaoral.com/pubmed/medoralv19_i5_p506.pdf	es