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Evaluation of holy basil mouthwash as an adjunctive plaque control agent in a four day plaque regrowth model

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Evaluation of holy basil mouthwash as an adjunctive plaque control agent in a four day plaque regrowth model

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dc.contributor.author Hosamane, Manasa es
dc.contributor.author Acharya, Anirudh B. es
dc.contributor.author Vij, Chhavi es
dc.contributor.author Trivedi, Dhiraj es
dc.contributor.author Setty, Swati B es
dc.contributor.author Thakur, Srinath L es
dc.date.accessioned 2015-01-20T09:11:49Z
dc.date.available 2015-01-20T09:11:49Z
dc.date.issued 2014 es
dc.identifier.citation Hosamane, Manasa ; Acharya, Anirudh B. ; Vij, Chhavi ; Trivedi, Dhiraj ; Setty, Swati B ; Thakur, Srinath L. Evaluation of holy basil mouthwash as an adjunctive plaque control agent in a four day plaque regrowth model. En: Journal of Clinical and Experimental Dentistry, 2014, Vol. 6, No. 5: 491-496 es
dc.identifier.uri http://hdl.handle.net/10550/41301
dc.description.abstract Objectives: Various antibacterial and antiplaque agents are used in chemical plaque control but none are without their shortcomings. Chlorhexidine considered a gold standard, also has an array of side effects. To overcome these, numerous herbal extracts have been tried and tested and one among them is holy basil. The present study evaluated the antibacterial efficacy of holy basil in vitro against some periodontopathogens and its antiplaque ef fect in vivo. Study Design: Thirty periodontally healthy volunteers were randomly divided into three groups and refrained from all mechanical oral hygiene measures for 4 days and used one of the randomly assigned mouthwash (1- chlor - hexidine; 2- holy basil; and 3- sterile water [placebo]) twice daily. The Plaque Index (PI) was assessed at days 0 and 5. Aqueous extract of holy basil was tested against Prevotella intermedia ( P. intermedia ) and Fusobacterium nucleatum ( F.nucleatum ). Results: Holy basil extract showed inhibition of both the tested periodontopathogens ( P.intermedia and F.nucleatum ) at various concentrations. In all groups, the PI increased from baseline to day 5. There was a statistically significant difference ( p < .05) between the chlorhexidine and placebo rinse and the holy basil and placebo rinse, but no statis - tically significant difference was found between the chlorhexidine and holy basil rinse with respect to PI. Conclusions: These results indicate that the holy basil mouthwash has an antiplaque effect and is efficacious against P. intermedia and F. nucleatum strains in vitro. Hence holy basil mouthwash may have potential as an antiplaque mouthwash with prophylactic benefits. en_US
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Evaluation of holy basil mouthwash as an adjunctive plaque control agent in a four day plaque regrowth model es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.type.hasVersion VoR es_ES

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