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The complete genome sequence of a 45,000 year old modern human from Western Siberia

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The complete genome sequence of a 45,000 year old modern human from Western Siberia

dc.contributor.author	Fu, Q.
dc.contributor.author	Li, H.
dc.contributor.author	Moorjani, P.
dc.contributor.author	Jay, F.
dc.contributor.author	Slepchenko, S.
dc.contributor.author	Bondarev, A.A.
dc.contributor.author	Johnson, P.L.F.
dc.contributor.author	Petri, A.A.
dc.contributor.author	Prüfer, K.
dc.contributor.author	de Filippo, C.
dc.contributor.author	Meyer, M.
dc.contributor.author	Zwyns, N.
dc.contributor.author	Salazar García, Domingo Carlos
dc.contributor.author	Kuzmin, Y.V.
dc.contributor.author	Keates, S.G.
dc.contributor.author	Kosintesev, P.A.
dc.contributor.author	Razhev, D.I.
dc.contributor.author	Richards, Michael P.
dc.contributor.author	Peristov, N.V.
dc.contributor.author	Lachmann, M.
dc.contributor.author	Douka, K.
dc.contributor.author	Higham, T.F.G.
dc.contributor.author	Slatkin, M.
dc.contributor.author	Hublin, J.J.
dc.contributor.author	Reich, D.
dc.contributor.author	Kelso, J.
dc.contributor.author	Viola, T.B.
dc.contributor.author	Pääbo, S.
dc.date.accessioned	2015-02-20T08:53:05Z
dc.date.available	2015-02-20T08:53:05Z
dc.date.issued	2014
dc.identifier.citation	Fu, Q. Li, H. Moorjani, P. Jay, F. Slepchenko, S. Bondarev, A.A. Johnson, P.L.F. Petri, A.A. Prüfer, K. de Filippo, C. Meyer, M. Zwyns, N. Salazar García, Domingo Carlos Kuzmin, Y.V. Keates, S.G. Kosintesev, P.A. Razhev, D.I. Richards, M.P. Peristov, N.V. Lachmann, M. Douka, K. Higham, T.F.G. Slatkin, M. Hublin, J.J. Reich, D. Kelso, J. Viola, T.B. Pääbo, S. 2014 The complete genome sequence of a 45,000 year old modern human from Western Siberia Nature 514 445 449
dc.identifier.uri	http://hdl.handle.net/10550/42071
dc.description.abstract	Wepresent the high-quality genome sequence of a 45,000-year-old modern human male from Siberia. This individual derives from a population that lived before¿or simultaneously with¿the separation of the populations in western and eastern Eurasia and carries a similar amount of Neanderthal ancestry as present-day Eurasians. However, the genomic segments of Neanderthal ancestry are substantially longer than those observed in present-day individuals, indicating that Neanderthal gene flow into the ancestors of this individual occurred 7,000¿13,000 years before he lived. We estimate an autosomal mutation rate of 0.4 x 10-9 to 0.6x10-9 per site per year, a Y chromosomal mutation rate of 0.7x10-9 to 0.9x10-9 per site per year based on the additional substitutions that have occurred in present-day non- Africans compared to this genome, and a mitochondrial mutation rate of 1.8x10-8 to 3.2x10-8 per site per year based on the age of the bone.
dc.language.iso	eng
dc.relation.ispartof	Nature, 2014, num. 514, p. 445-449
dc.subject	Prehistòria
dc.title	The complete genome sequence of a 45,000 year old modern human from Western Siberia
dc.type	journal article	es_ES
dc.date.updated	2015-02-20T08:53:05Z
dc.identifier.doi	10.1038/nature13810
dc.identifier.idgrec	101659
dc.rights.accessRights	open access	es_ES