A retrospective study of 72 cases diagnosed with idiopathic trigeminal neuralgia in indian populace
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Yadav, Sunil; Mittal, Hitesh-Chander; Sachdeva, Akash; Verma, Ajay; Dhupar, Vikas; Dhupar, Anita
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Aquest document és un/a article, creat/da en: 2015
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Context: Trigeminal neuralgia is as a chronic, debilitating condition, which can have a major impact on quality of
life. There are few reports of trigeminal neuralgia in oriental populations.
Objectives: To evaluate the retrospective data of the patients diagnosed with idiopathic trigeminal neuralgia and to
understanding the disorder in the Indian populace.
Methods: The retrospective data of 72 patients with typical idiopathic trigeminal neuralgia regarding age of onset,
gender, site of involvement, clinical presentations and treatment received during three years of the follow up was
collected and analyzed.
Results: In the present retrospective study, the mean age was 54.9 years; female to male ratio was 2.13:1; rural to
urban ratio 1.76:1 with 62.5% suffered trigeminal neuralgic pain on the right side. Carbamazepine was found to be
highly effective in 60.8% of the cases on long-term basis with maintenance doses. Other treatment modalities were
employed in more refractory cases including add-on of gabapentin, which relieved the symptoms for an additional
duration of 13±3months. The neurolytic alcohol bloc was given in 30% of patients who stopped responding to com
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bination of carbamazepine and gabapentin and relieved pain for a mean duration of 17.25±2.95 months. Twenty
three percent of the patients (23%) required peripheral neurectomy.
Conclusions: Carbamazepine was found to be highly effective in trigeminal neuralgia. Other treatment modality
includes add-on of gabapentin, neurolytic alcohol blocs and peripheral surgical intervention in more refractory
cases. Only limited cases needed further neurological consideration.
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