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Visual fields in a chloroquine treatment

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Visual fields in a chloroquine treatment

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dc.contributor.author	García Domene, María del Carmen
dc.contributor.author	Díez Ajenjo, María Amparo
dc.contributor.author	Fez Saiz, Dolores de
dc.contributor.author	Luque Cobija, María Josefa
dc.date.accessioned	2015-02-26T13:12:23Z
dc.date.available	2015-02-26T13:12:23Z
dc.date.issued	2014
dc.identifier.citation	García Domene, María del Carmen Díez Ajenjo, María Amparo Fez Saiz, Dolores de Luque Cobija, María Josefa 2014 Visual fields in a chloroquine treatment Clinical optometry (Auckland) 6 59 70
dc.identifier.uri	http://hdl.handle.net/10550/42427
dc.description.abstract	Purpose: In this study, we describe contrast sensitivity losses in the visual field of a patient affected by chloroquine toxicity, measured with stimuli favoring different visual mechanisms. We have compared these results with those of other, usual clinical tests. Methods: The vision of a patient who underwent ten years of chloroquine treatment was analyzed by a battery of clinical tests: visual acuity (VA), Amsler¿s grid, Farnsworth¿Munsell 100-hue test, spectral domain optical coherence tomography, multifocal electroretinogram (ERG), white-on-white and red-on-white Humphrey perimetries, chromatic and achromatic contrast sensitivity perimetry tests, and fluorescein angiography. Measurements were taken just before the cessation of the treatment, and 6 months later. Results: The subjective visual perception of the patient was worse (in comparison with the rest of the visual field at the time of the first visit) in the center of the visual field, and was impaired on the second visit. Although standard automated perimetry (SAP) was practically normal and ERG results did not worsen with time, VA, Amsler¿s grid, and visual fields with stimuli favoring the magnocellular and chromatic pathways signalled progressive loss of visual function. Conclusions: Standard tests such as SAP or ERG may not detect visual field losses or progression of existing visual losses in a case of chloroquine toxicity, whereas tests evaluating contrast sensitivity with stimuli favoring different visual mechanisms may be more sensitive.
dc.language.iso	eng
dc.relation.ispartof	Clinical optometry (Auckland), 2014, vol. 6, p. 59-70
dc.subject	Visió
dc.subject	Retina
dc.subject	Òptica
dc.title	Visual fields in a chloroquine treatment
dc.type	journal article	es_ES
dc.date.updated	2015-02-26T13:12:23Z
dc.identifier.doi	10.2147/OPTO.S63532
dc.identifier.idgrec	099688
dc.rights.accessRights	open access	es_ES