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Efect of periodontal disease and non surgical periodontal treatment on C-reactive protein. Evaluation of type 1 diabetic patient.

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Efect of periodontal disease and non surgical periodontal treatment on C-reactive protein. Evaluation of type 1 diabetic patient.

dc.contributor.author	Llambés Arenas, Fernando
dc.contributor.author	Silvestre Donat, Francisco Javier
dc.contributor.author	Hernández Mijares, Antonio
dc.contributor.author	Guiha, Rami
dc.contributor.author	Bautista, Daniel
dc.contributor.author	Caffesse, Raul G.
dc.date.accessioned	2015-03-05T09:03:54Z
dc.date.available	2015-03-05T09:03:54Z
dc.date.issued	2012
dc.identifier.citation	Llambés Arenas, Fernando; Silvestre, Francisco Javier; Hernández Mijares, Antonio; Guiha, Rami Bautista, Daniel; Caffesse, Raúl (2012) Efect of periodontal disease and non surgical periodontal treatment on C-reactive protein. Evaluation of type 1 diabetic patient. Medicina Oral Patologia Oral y Cirugia Bucal 17 4 e562 e568
dc.identifier.uri	http://hdl.handle.net/10550/42611
dc.description.abstract	Objectives: The purpose of this study was to analyze how anti-infectious periodontal treatment affects C reactive protein (CRP) values in patients with type 1 diabetes, and correlate baseline CRP levels with periodontal disease severity. Study Design: A cohort of fifty three subjects with type 1 diabetes and moderate to severe periodontitis were recruited. Periodontal parameters were measured, and blood samples were obtained to evaluate high-sensitivity C-reactive protein (hs-CRP). Group 1 was treated with scaling, root planning, and systemic administration of doxycycline. Group 2 received only scaling and root planning. Results: Hs-CRP was reduced after periodontal treatment in group 1 (-0.22 mg/l) and 2 (-0.21 mg/l ) but this reduction was not statistically significant, even in the patients with the best response to periodontal treatment. However, significant correlation appeared between hs-CRP and mean probing pocket depth (PPD) (p=0, 01) and mean clinical attachment level (CAL) (p=0,03). Conclusions: Non-surgical periodontal treatment couldn¿t reduce hs-CRP values, however, it was found an asso- ciation between advanced periodontitis and elevated blood hs-CRP levels in patients with type 1 diabetes. It can be speculated that periodontal disease increases production of pro-inflammatory mediators in patients with type 1 diabetes, but other producing sources of these pro-inflammatory substances may exist.
dc.relation.ispartof	Medicina Oral Patologia Oral y Cirugia Bucal, 2012, vol. 17, num. 4, p. e562-e568
dc.subject	Estomatologia
dc.subject	Diabetis
dc.subject	Cirurgia dental
dc.title	Efect of periodontal disease and non surgical periodontal treatment on C-reactive protein. Evaluation of type 1 diabetic patient.
dc.type	journal article	es_ES
dc.date.updated	2015-03-05T09:03:54Z
dc.identifier.doi	10.4317/medoral.17793
dc.identifier.idgrec	087466
dc.rights.accessRights	open access	es_ES