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Difficulties detecting miRNA-203 in human whole saliva by the use of PCR
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- Medicina oral, patología oral y cirugía bucal. Ed inglesa
- Medicina oral, patología oral y cirugía bucal. Ed inglesa. 2015. Vol. 20, no. 2
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Difficulties detecting miRNA-203 in human whole saliva by the use of PCR
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| dc.contributor.author | Lundegard, Martin | es |
| dc.contributor.author | Nylander, Karin | es |
| dc.contributor.author | Danielsson, Karin | es |
| dc.date.accessioned | 2015-05-27T11:50:18Z | |
| dc.date.available | 2015-05-27T11:50:18Z | |
| dc.date.issued | 2015 | es |
| dc.identifier.citation | Lundegard, Martin ; Nylander, Karin ; Danielsson, Karin. Difficulties detecting miRNA-203 in human whole saliva by the use of PCR. En: Medicina oral, patología oral y cirugía bucal. Ed inglesa, 2015, Vol. 20, No. 2: 4- | es |
| dc.identifier.uri | http://hdl.handle.net/10550/44074 | |
| dc.description.abstract | Objectives: Oral Lichen Planus (OLP) is a chronic disease of the oral mucosa, and according to the WHO also a pre malignant condition. Micro-RNAs are short non coding RNAs capable of regulating mRNA expression. MiRNA:scan be detected in tissue, blood and human whole saliva (HWS) and recently we have shown miR-203 to be up-regulated in tissue from OLP lesions. Study Design: In order to see whether mRNA as well as miR-203 could be detected also in HWS, saliva from healthy controls and patients with OLP were analysed using two different PCR methods. Results: Results showed low mRNA and miRNA levels in general in HWS samples, making it hard to generate conclusive results. Conclusions: In order to make HWS a valuable source for different analyses, more sensitive PCR techniques capable of detecting very low levels of mRNAand miRNAas well as more efficient methods for extraction of RNA are needed. | en_US |
| dc.subject | Odontología | es |
| dc.subject | Ciencias de la salud | es |
| dc.title | Difficulties detecting miRNA-203 in human whole saliva by the use of PCR | es |
| dc.type | journal article | es_ES |
| dc.subject.unesco | UNESCO::CIENCIAS MÉDICAS | es |
| dc.type.hasVersion | VoR | es_ES |
| dc.identifier.url | http://dialnet.unirioja.es/servlet/citart?info=link&codigo=5081401&orden=0 | es |
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