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Application of mesenchymal stem cells in bone regenerative procedures in oral implantology. A literature review

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Application of mesenchymal stem cells in bone regenerative procedures in oral implantology. A literature review

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dc.contributor.author Viña Almunia, José es_ES
dc.contributor.author El Alami, Marya es_ES
dc.contributor.author Gambini Ricapa, Juan es_ES
dc.contributor.author Borrás Blasco, Consuelo es_ES
dc.contributor.author Viña, Jose es_ES
dc.contributor.author Peñarrocha, María A. es_ES
dc.date.accessioned 2015-06-10T08:35:43Z
dc.date.available 2015-06-10T08:35:43Z
dc.date.issued 2014
dc.identifier.citation Journal of Clinical and Experimental Dentistry Vol. 6 Issue 1: pp. e60-e65 es_ES
dc.identifier.uri http://hdl.handle.net/10550/44277
dc.description.abstract Objective: The aim of this work was to review de literature about the role of mesenchymal stem cells in bone regenerative procedures in oral implantology, specifically, in the time require to promote bone regeneration. Study Design: A bibliographic search was carried out in PUBMED with a combination of different key words. Animal and human studies that assessed histomorphometrically the influence of mesenchymal stem cells on bone regeneration procedures in oral implantology surgeries were examined. Reults: - Alveolar regeneration: Different controlled histomorphometric animal studies showed that bone regeneration is faster using stem cells seeded in scaffolds than using scaffolds or platelet rich plasma alone. Human studies revealed that stem cells increase bone regeneration. - Maxillary sinus lift: Controlled studies in animals and in humans showed higher bone regeneration applying stem cells compared with controls. - Periimplantary bone regeneration and alveolar distraction: Studies in animals showed higher regeneration when stem cells are used. In humans, no evidence of applying mesenchymal stem cells in these regeneration procedures was found. Conclusion: Stem cells may promote bone regeneration and be useful in bone regenerative procedures in oral implantology, but no firm conclusions can be drawn from the rather limited clinical studies so far performed. Key words:Mesenchymal stem cells, bone regeneration, dental implants, oral surgery, tissue engineering. es_ES
dc.title Application of mesenchymal stem cells in bone regenerative procedures in oral implantology. A literature review es_ES
dc.type journal article es_ES
dc.identifier.doi 10.4317/jced.51186 es_ES
dc.identifier.idgrec 097499 es_ES

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