NAGIOS: RODERIC FUNCIONANDO

Frequency of nut consumption and mortality risk in the PREDIMED nutrition intervention trial

Repositori DSpace/Manakin

IMPORTANT: Aquest repositori està en una versió antiga des del 3/12/2023. La nova instal.lació está en https://roderic.uv.es/

Frequency of nut consumption and mortality risk in the PREDIMED nutrition intervention trial

dc.contributor.author	Guasch-Ferré, Marta	es_ES
dc.contributor.author	Bulló, Mònica	es_ES
dc.contributor.author	Martínez-González, Miguel Ángel	es_ES
dc.contributor.author	Ros, Emilio	es_ES
dc.contributor.author	Corella, Dolores	es_ES
dc.contributor.author	Estruch, Ramón	es_ES
dc.contributor.author	Fitó, Montserrat	es_ES
dc.contributor.author	Arós, Fernando	es_ES
dc.contributor.author	Wärnberg, Julia	es_ES
dc.contributor.author	Fiol, Miquel	es_ES
dc.contributor.author	Lapetra, José	es_ES
dc.contributor.author	Vinyoles, Ernest	es_ES
dc.contributor.author	Lamuela-Raventós, Rosa Maria	es_ES
dc.contributor.author	Serra-Majem, Lluís	es_ES
dc.contributor.author	Pintó, Xavier	es_ES
dc.contributor.author	Ruiz-Gutiérrez, Valentina	es_ES
dc.contributor.author	Basora, Josep	es_ES
dc.contributor.author	Salas-Salvadó, Jordi	es_ES
dc.date.accessioned	2015-06-19T07:47:44Z
dc.date.available	2015-06-19T07:47:44Z
dc.date.issued	2013	es_ES
dc.identifier.citation	BMC Medicine Vol. 11 pp. 164-164	es_ES
dc.identifier.uri	http://hdl.handle.net/10550/44497
dc.description.abstract	BackgroundProspective studies in non-Mediterranean populations have consistently related increasing nut consumption to lower coronary heart disease mortality. A small protective effect on all-cause and cancer mortality has also been suggested. To examine the association between frequency of nut consumption and mortality in individuals at high cardiovascular risk from Spain, a Mediterranean country with a relatively high average nut intake per person.MethodsWe evaluated 7,216 men and women aged 55 to 80 years randomized to 1 of 3 interventions (Mediterranean diets supplemented with nuts or olive oil and control diet) in the PREDIMED (‘PREvención con DIeta MEDiterránea’) study. Nut consumption was assessed at baseline and mortality was ascertained by medical records and linkage to the National Death Index. Multivariable-adjusted Cox regression and multivariable analyses with generalized estimating equation models were used to assess the association between yearly repeated measurements of nut consumption and mortality.ResultsDuring a median follow-up of 4.8 years, 323 total deaths, 81 cardiovascular deaths and 130 cancer deaths occurred. Nut consumption was associated with a significantly reduced risk of all-cause mortality (P for trend <0.05, all). Compared to non-consumers, subjects consuming nuts >3 servings/week (32% of the cohort) had a 39% lower mortality risk (hazard ratio (HR) 0.61; 95% CI 0.45 to 0.83). A similar protective effect against cardiovascular and cancer mortality was observed. Participants allocated to the Mediterranean diet with nuts group who consumed nuts >3 servings/week at baseline had the lowest total mortality risk (HR 0.37; 95% CI 0.22 to 0.66).ConclusionsIncreased frequency of nut consumption was associated with a significantly reduced risk of mortality in a Mediterranean population at high cardiovascular risk.Please see related commentary: http://www.biomedcentral.com/1741-7015/11/165.Trial registrationClinicaltrials.gov. International Standard Randomized Controlled Trial Number (ISRCTN): 35739639. Registration date: 5 October 2005.	es_ES
dc.subject	Cancer	es_ES
dc.subject	Cardiovascular	es_ES
dc.subject	Mortality	es_ES
dc.subject	Nuts	es_ES
dc.subject	PREDIMED study	es_ES
dc.title	Frequency of nut consumption and mortality risk in the PREDIMED nutrition intervention trial	es_ES
dc.type	journal article	es_ES
dc.identifier.doi	10.1186/1741-7015-11-164	es_ES
dc.identifier.idgrec	094235	es_ES