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Replicating phages in the epidermal mucosa of the eel (anguilla anguilla)

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Replicating phages in the epidermal mucosa of the eel (anguilla anguilla)

dc.contributor.author	Carda Diéguez, Miguel
dc.contributor.author	Megumi Mizuno, Carolina
dc.contributor.author	Ghai, Rohit
dc.contributor.author	Rodríguez Valera, Francisco Eduardo
dc.contributor.author	Amaro González, Carmen
dc.date.accessioned	2015-09-02T08:06:56Z
dc.date.available	2015-09-02T08:06:56Z
dc.date.issued	2015
dc.identifier.citation	Carda Diéguez, Miguel; Megumi Mizuno, Carolina; Ghai, Rohit; Rodríguez Valera, Francisco Eduardo; Amaro González, Carmen (2015) Replicating phages in the epidermal mucosa of the eel (anguilla anguilla) Frontiers In Microbiology 6 3-1 3-10
dc.identifier.uri	http://hdl.handle.net/10550/46804
dc.description.abstract	n this work, we used the eel (Anguilla anguilla) as an animal model to test the hypothesis of Barr et al. (2013a,b) about the putative role of the epidermal mucosa as a phage enrichment layer. To this end, we analyzed the microbial content of the skin mucus of wild and farmed eels by using a metagenomic approach. We found a great abundance of replicating phage genomes (concatemers) in all the samples. They were assembled in four complete genomes of three Myovirus and one Podovirus. We also found evidences that ΦKZ and Podovirus phages could be part of the resident microbiota associated to the eel mucosal surface and persist on them over the time. Moreover, the viral abundance estimated by epiflorescent counts and by metagenomic recruitment from eel mucosa was higher than that of the surrounding water. Taken together, our results support the hypothesis that claims a possible role of phages in the animal mucus as agents controlling bacterial populations, including pathogenic species, providing a kind of innate immunity.
dc.language.iso	eng
dc.relation.ispartof	Frontiers In Microbiology, 2015, vol. 6, p. 3-1-3-10
dc.subject	Microbiologia
dc.subject	Peixos
dc.subject	Bacteris patògens
dc.title	Replicating phages in the epidermal mucosa of the eel (anguilla anguilla)
dc.type	journal article	es_ES
dc.date.updated	2015-09-02T08:06:56Z
dc.identifier.doi	10.3389/fmicb.2015.00003
dc.identifier.idgrec	104028
dc.rights.accessRights	open access	es_ES