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Systemic moxifloxacin vs amoxicillin/metronidazole adjunct to non-surgical treatment in generalized aggressive periodontitis

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Systemic moxifloxacin vs amoxicillin/metronidazole adjunct to non-surgical treatment in generalized aggressive periodontitis

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dc.contributor.author Guzeldemir, Esra es
dc.contributor.author Gürgan, Cem Abdulkadir es
dc.date.accessioned 2015-09-21T08:41:01Z
dc.date.available 2015-09-21T08:41:01Z
dc.date.issued 2015 es
dc.identifier.citation Guzeldemir, Esra ; Gürgan, Cem Abdulkadir . Systemic moxifloxacin vs amoxicillin/metronidazole adjunct to non-surgical treatment in generalized aggressive periodontitis. En: Medicina oral, patología oral y cirugía bucal. Ed inglesa, 2015, Vol. 20, No. 4: 9- es
dc.identifier.uri http://hdl.handle.net/10550/47170
dc.description.abstract Background: The objective of this randomized clinical study was to evaluate the effect of systemic administration of moxifloxacin compared to amoxicillin and metronidazole, combined with non-surgical treatment in patients with generalized aggressive periodontitis (GAgP) in a 6-month follow-up. Material and Methods: A total of 39 systemically healthy patients with GAgP were evaluated in this randomized clinical trial. Periodontal parameters were recorded at the baseline during the 1 st , 3 rd and 6 th month. Patients received either 400 mg of moxifloxacin per os once daily or 500 mg of metronidazole and 500 mg amoxicillin per os three times daily for 7 days consecutively. Results: No significant differences between groups were found in any parameters at the baseline. Both groups led to a statistically significant decrease in all clinical periodontal parameters compared to the baseline (PI, p <0.001 and GI, PD, BOP, CAL, p<0.01). There were no differences between the 1 st and 3 rd months or the 3 rd and 6 th months for clinical parameters in the groups. Also, no intergroup difference was observed in any parameters at any time, except the gingival index at 6 th months. Conclusions: Systemic administration of moxifloxacin as an adjunct to non-surgical treatment significantly improves clinical outcomes and provides comparable clinical improvement with less adverse events to that of combination of amoxicillin and metronidazole in the treatment of GAgP. en_US
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Systemic moxifloxacin vs amoxicillin/metronidazole adjunct to non-surgical treatment in generalized aggressive periodontitis es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.type.hasVersion VoR es_ES
dc.identifier.url http://dialnet.unirioja.es/servlet/citart?info=link&codigo=5177686&orden=0 es

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