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Correlation of Zinc with Oxidative Stress Biomarkers

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Correlation of Zinc with Oxidative Stress Biomarkers

dc.contributor.author	Morales Suárez-Varela, María M.
dc.contributor.author	Llopis González, Agustín
dc.contributor.author	González Albert, Verónica
dc.contributor.author	López Izquierdo, Raúl
dc.contributor.author	González Manzano, Isabel
dc.contributor.author	Chaves Martínez, Felipe Javier
dc.contributor.author	Huerta Biosca, Vicente
dc.contributor.author	Martín Escudero, Juan Carlos
dc.date.accessioned	2015-09-23T11:38:18Z
dc.date.available	2015-09-23T11:38:18Z
dc.date.issued	2015
dc.identifier.citation	MoralesSuárez-Varela, María Llopis González, Agustín González Albert, Verónica López Izquierdo, Raúl González Manzano, Isabel Cháves, Javier Huerta Biosca, Vicente Martin Escudero, Juan Carlos 2015 Correlation of Zinc with Oxidative Stress Biomarkers International Journal Of Environmental Research And Public Health 12 3060 3076
dc.identifier.uri	http://hdl.handle.net/10550/47200
dc.description.abstract	Hypertension and smoking are related with oxidative stress (OS), which in turn reports on cellular aging. Zinc is an essential element involved in an individual¿s physiology. The aim of this study was to evaluate the relation of zinc levels in serum and urine with OS and cellular aging and its effect on the development of hypertension. In a Spanish sample with 1500 individuals, subjects aged 20¿59 years were selected, whose zinc intake levels fell within the recommended limits. These individuals were classified found (Pearson¿s C = 0.639; p = 0.01) between Zn serum/urine quotient and oxidized glutathione levels (GSSG). Finally, risk of hypertension significantly increased when the GSSG levels exceeded the 75 percentile; OR = 2.80 (95%CI = 1.09¿7.18) and AOR = 3.06 (95%CI = 0.96¿9.71). Low zinc levels in serum were related with OS and cellular aging and were, in turn, to be a risk factor for hypertension.
dc.language.iso	eng
dc.relation.ispartof	International Journal Of Environmental Research And Public Health, 2015, vol. 12, p. 3060-3076
dc.subject	Salut pública
dc.subject	Farmacologia
dc.title	Correlation of Zinc with Oxidative Stress Biomarkers
dc.type	journal article	es_ES
dc.date.updated	2015-09-23T11:38:18Z
dc.identifier.doi	10.3390/ijerph120303060
dc.identifier.idgrec	103150
dc.rights.accessRights	open access	es_ES