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Influence of perioperative dexamethasone on delayed union in mandibular fractures: a clinical and radiological study

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Influence of perioperative dexamethasone on delayed union in mandibular fractures: a clinical and radiological study

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dc.contributor.author Snäll, Johanna es
dc.contributor.author Apajalahti, Satu es
dc.contributor.author Suominen-Taipale, Anna-Liisa es
dc.contributor.author Törnwall, Jyrki es
dc.contributor.author Thorén, Hanna es
dc.date.accessioned 2015-11-23T13:40:20Z
dc.date.available 2015-11-23T13:40:20Z
dc.date.issued 2015 es
dc.identifier.citation Snäll, Johanna ; Apajalahti, Satu ; Suominen-Taipale, Anna-Liisa ; Törnwall, Jyrki ; Thorén, Hanna. Influence of perioperative dexamethasone on delayed union in mandibular fractures: a clinical and radiological study. En: Medicina oral, patología oral y cirugía bucal. Ed inglesa, 2015, Vol. 20, No. 5: 13- es
dc.identifier.uri http://hdl.handle.net/10550/48334
dc.description.abstract Background: The aim was to clarify the occurrence of delayed union after surgical treatment of mandibular fracture and investigate whether an association exists between perioperative use of dexamethasone and delayed union. Material and Methods: Thirty-seven patients were included in a prospective randomized study. Of these patients, 19 (51.4%) were randomized to receive a total dose of 30 mg of dexamethasone and 18 (48.6%) served as controls. Patients underwent clinical and radiological investigation immediately, one month, three months and six months postoperatively. Radiographs were evaluated by an experienced, blinded senior oral radiologist. Results: Delayed fracture union was found in 9 patients (24.3%). It was associated significantly with angle fractures (p=0.012). Delayed union occurred more frequently in patients who received dexamethasone (36.8%) than in those who did not (11.1%) (p=0.068). The association of infection with delayed union was significan t ( p=0.027). Moreover, dexamethasone was significantly ( p=0.019) associated with delayed fracture union with concomitant infection. Gender, age group, smoking habit, treatment delay and duration of surgery were not associated with delayed union. Conclusions: Infection was associated with delayed union. Short-term high-dose dexamethasone predisposed to complicated fracture union, especially in patients with angle fractures. The relationship between dexamethasone and delayed bone healing without infection remains unresolved en_US
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Influence of perioperative dexamethasone on delayed union in mandibular fractures: a clinical and radiological study es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.type.hasVersion VoR es_ES
dc.identifier.url http://dialnet.unirioja.es/servlet/citart?info=link&codigo=5219422&orden=0 es

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