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Serologic control against hepatitis B virus among dental students of the University of Granada, Spain

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Serologic control against hepatitis B virus among dental students of the University of Granada, Spain

dc.contributor.author	Arias Moliz, María Teresa	es
dc.contributor.author	Rojas, Laura	es
dc.contributor.author	Liébana Cabanillas, Francisco	es
dc.contributor.author	Bernal, Carmen	es
dc.contributor.author	Castillo, Francisca	es
dc.contributor.author	Rodriguez Archilla, Alberto	es
dc.contributor.author	Castillo, Ana	es
dc.contributor.author	Liébana Ureña, José	es
dc.date.accessioned	2015-11-23T13:41:43Z
dc.date.available	2015-11-23T13:41:43Z
dc.date.issued	2015	es
dc.identifier.citation	Arias Moliz, María Teresa ; Rojas, Laura ; Liébana Cabanillas, Francisco ; Bernal, Carmen ; Castillo, Francisca ; Rodriguez Archilla, Alberto ; Castillo, Ana ; Liébana Ureña, José. Serologic control against hepatitis B virus among dental students of the University of Granada, Spain. En: Medicina oral, patología oral y cirugía bucal. Ed inglesa, 2015, Vol. 20, No. 5: 9-	es
dc.identifier.uri	http://hdl.handle.net/10550/48346
dc.description.abstract	Background: To evaluate the immunological situation against hepatitis B virus (HBV) of a cohort of dentistry students, to analyze the behavior of the levels of hepatitis B surface antigen (anti-HBs) after the administration of one or three vaccine doses, and to determine the influence of age and sex on the immune response. Material and Methods: This retrospective cohort study included students attending the School of Dentistry of the institution where the study was performed from 2005 to 2012 who had completed the public health vaccination calendar for HBV at the age of 12-13. Data on age, sex, basal anti-HBs levels, post-vaccination anti-HBs results and final anti-HBs levels were collected. Comparisons of the basal and final levels, as well as associations regarding age and sex, were performed by means of the Student t and Chi-square tests. Results: Of the 359 students, 97 (27.02%) had basal antibody concentrations <10 mIU/ml, whereas in 262 the levels of anti-HBs were ≥10 mIU/ml (72.98%). Of the 288 participating students who completed the School ́s protocol for immunization, 287 (99.65%) attained a level of protection ≥10 mIU/ml. Globally, there were statistically significant differences between the basal antibody levels and those achieved after administration of the vaccine and booster, but no association with age or sex was observed. Conclusions: About 70% of dental students vaccinated as preadolescents had serologic evidence of protection against HBV. Administering a booster is associated with the presence of an excellent immune memory. There is clearly a need to reinforce control of the antibody levels in groups at risk, such as Dentistry students	en_US
dc.subject	Odontología	es
dc.subject	Ciencias de la salud	es
dc.title	Serologic control against hepatitis B virus among dental students of the University of Granada, Spain	es
dc.type	journal article	es_ES
dc.subject.unesco	UNESCO::CIENCIAS MÉDICAS	es
dc.type.hasVersion	VoR	es_ES
dc.identifier.url	http://dialnet.unirioja.es/servlet/citart?info=link&codigo=5219417&orden=0	es