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Estimation of Pyruvic acid in serum and saliva among healthy and potentially malignant disorder subjects – a stepping stone for cancer screening?

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Estimation of Pyruvic acid in serum and saliva among healthy and potentially malignant disorder subjects – a stepping stone for cancer screening?

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dc.contributor.author Bhat, Anithraj es
dc.contributor.author Bhat, Manohara es
dc.contributor.author Prasad, Kakarla es
dc.contributor.author Trivedi, Dhiraj es
dc.contributor.author Acharya, Swathi es
dc.date.accessioned 2015-11-23T13:53:19Z
dc.date.available 2015-11-23T13:53:19Z
dc.date.issued 2015 es
dc.identifier.citation Bhat, Anithraj ; Bhat, Manohara ; Prasad, Kakarla ; Trivedi, Dhiraj ; Acharya, Swathi. Estimation of Pyruvic acid in serum and saliva among healthy and potentially malignant disorder subjects – a stepping stone for cancer screening?. En: Journal of Clinical and Experimental Dentistry, 2015, Vol. 7, No. 4: 462-465 es
dc.identifier.uri http://hdl.handle.net/10550/48351
dc.description.abstract Background: According to Warburg’s effect, the rate of glycolysis increases in cancerous cells. This will increase overall levels of pyruvic acid. The present on-going study was conducted to estimate the levels of pyruvic acid in saliva and serum in normal, oral PMD subjects. Material and Methods: A total of 50 subjects in healthy, PMD of the oral cavity individuals were selected based on clinical and histological criteria. Collected saliva and serum samples were subjected to pyruvic acid level estimation using biochemical analysis. Results: Of the 50 participants 25 (13: Males; 12: Females) & 25 (16: Males; 9: Females) were PMD group. Independent samples t test showed statistically significant difference in serum & salivary pyruvic acid level in between 2 groups ( P < 0.001 respectively) Conclusions: Estimation of pyruvic acid showed sequential increase in the level in PMD group compared to healthy. Hence the study results open new direction in cancer screening. en_US
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Estimation of Pyruvic acid in serum and saliva among healthy and potentially malignant disorder subjects – a stepping stone for cancer screening? es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.type.hasVersion VoR es_ES

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