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Hemodynamic changes following injection of local anesthetics with different concentrations of epinephrine during simple tooth extraction: a prospective randomized clinical trial

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Hemodynamic changes following injection of local anesthetics with different concentrations of epinephrine during simple tooth extraction: a prospective randomized clinical trial

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dc.contributor.author Abu-Mostafa, Nedal es
dc.contributor.author Al Showaikhat, Fatimah es
dc.contributor.author Al Shubbar, Fatimah es
dc.contributor.author Al Zawad, Kawther es
dc.contributor.author Al Banawi, Fatimah es
dc.date.accessioned 2015-11-23T13:53:19Z
dc.date.available 2015-11-23T13:53:19Z
dc.date.issued 2015 es
dc.identifier.citation Abu-Mostafa, Nedal ; Al Showaikhat, Fatimah ; Al Shubbar, Fatimah ; Al Zawad, Kawther ; Al Banawi, Fatimah. Hemodynamic changes following injection of local anesthetics with different concentrations of epinephrine during simple tooth extraction: a prospective randomized clinical trial. En: Journal of Clinical and Experimental Dentistry, 2015, Vol. 7, No. 4: 471-476 es
dc.identifier.uri http://hdl.handle.net/10550/48353
dc.description.abstract Background: Presence of epinephrine in local anesthetic cartridge increases the duration of local anesthesia (LA), decreases the risk of toxicity, and provides hemostasis. However, the unfavorable effects are increasing heart rate (HR) and raising blood pressure (BP). The aim was to evaluate hemodynamic changes in the BP, HR, and oxygen saturation (SpO2) of normal patients undergoing tooth extraction using LA with various epinephrine concentrations. Material and Methods: A prospective randomized clinical trial was conducted on 120 patients who were divided randomly into 3 parallel groups according to the LA received. Group 1: lidocaine 2% with epinephrine 1:80,000 (L80). Group 2: articaine 4% with epinephrine 1:100,000 (A100). Group 3: articaine 4% with epinephrine 1:200,000 (A200). Inclusion criteria: normal patients whose BP < 140/90. Exclusion criteria: hypertension, cardiovascular disease, hyperthyroidism, pregnancy, and allergy to LA. BP, HR, and (SpO2) were evaluated in 3 different time points: 3 minutes before LA, 3 minutes after LA, and 3 minutes after extraction. Results: Systolic blood pressure (SBP) significantly increased after injection of L80 and continued after extraction to be significant than pre-injection. SBP significantly increased after injection of A100 then decreased after extraction. In the group of A200, SBP insignificantly decreased after injection then increased after extraction. The increasing of SBP between time point 1and 2 was significantly higher in G1 than G3 ( p =0.014). Diastolic blood pressure decreased after LA in the 3 groups; however it was significant only with L80, then increased after extraction for all. Conclusions: The changings of DBP, HR and SpO2 after anesthesia and extraction showed no significant difference among the three groups. However, A200 had significant lesser effect on SBP than L80 and the least effect on other parameters. Therefore, A200 is considered safer than L80 and A100 and is recommended for LA before teeth extraction in normal patient. en_US
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Hemodynamic changes following injection of local anesthetics with different concentrations of epinephrine during simple tooth extraction: a prospective randomized clinical trial es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.type.hasVersion VoR es_ES

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