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Salivary gland dysfunction markers in type 2 diabetes mellitus patients

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Salivary gland dysfunction markers in type 2 diabetes mellitus patients

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dc.contributor.author Aitken Saavedra, Juan es
dc.contributor.author Rojas Alcayaga, Gonzalo es
dc.contributor.author Maturana Ramírez, Andrea es
dc.contributor.author Escobar Álvarez, Alejandro es
dc.contributor.author Cortes Coloma, Andrea es
dc.contributor.author Reyes Rojas, Montserrat es
dc.contributor.author Viera Sapiain, Valentina es
dc.contributor.author Villablanca Martínez, Claudia es
dc.contributor.author Morales Bozo, Irene es
dc.date.accessioned 2015-11-23T13:53:20Z
dc.date.available 2015-11-23T13:53:20Z
dc.date.issued 2015 es
dc.identifier.citation Aitken Saavedra, Juan ; Rojas Alcayaga, Gonzalo ; Maturana Ramírez, Andrea ; Escobar Álvarez, Alejandro ; Cortes Coloma, Andrea ; Reyes Rojas, Montserrat ; Viera Sapiain, Valentina ; Villablanca Martínez, Claudia ; Morales Bozo, Irene. Salivary gland dysfunction markers in type 2 diabetes mellitus patients. En: Journal of Clinical and Experimental Dentistry, 2015, Vol. 7, No. 4: 501-505 es
dc.identifier.uri http://hdl.handle.net/10550/48358
dc.description.abstract Background: Diabetes mellitus (DM) is a chronic disease of the carbohydrate metabolism that, when not rigorously controlled, compromises systemic and organ integrity, thereby causing renal diseases, blindness, neuropathy, arteriosclerosis, infections, and glandular dysfunction, including the salivary glands. The aim of this study was to determine the relationship between the qualitative and quantitative parameters of salivary alteration, which are indicators of salivary gland dysfunction, and the level of metabolic control of type 2 diabetes patients. Material and Methods: A convenience sample of 74 voluntary patients with type 2 DM was selected, each of whom donated a sample of unstimulated saliva. Salivary parameters such as salivary flow rate, protein concentration, pH, and xerostomia were studied. Results: There is a positive relationship between the level of metabolic control measured with HbA1 and the protein concentration in saliva (Spearman rho = 0.329 and p = 0.004). The same assay showed an inverse correlation between HbA1 and pH (Spearman rho = -0.225 and p = 0.05). Conclusions: The protein concentration in saliva and, to a lesser extent, the pH may be useful as glandular dysfunction indicators in DM2 patients. en_US
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Salivary gland dysfunction markers in type 2 diabetes mellitus patients es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.type.hasVersion VoR es_ES

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