ABSTRACT <br> Background and Objectives: Lifespan is getting longer at a global level. More people, therefore, live past 65 years of age. Ageing favors frailty, a condition that makes the body more susceptible to diseases. We present updated information of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA), and particularly, the Cognitive Decline (CD) group in Action Group 3 (A3), focused in the prevention of frailty and functional decline. Moreover, details of one of the commitments in CD, which deals with the specificities of women in frailty and ageing (Chronic Ailment Reduction after Menopause, CARMEN), will be presented as well. Objectives of EIPAHA are to increase life expectancy of European citizens in two years by 2020 and to improve their quality of life. Methods: We revised literature and the web of the European Commission in what refers to EIP on AHA, A3 action group, and CD. Furthermore, we have summarized the main aspects of the CARMEN commitment. Results: We have sketched the main traits of the selected targets. A series of measures has been taken for favoring prevention of frailty and for health promotion of elderly people; this will help to increase the Europeans average healthy lifespan by two years under conditions of improved quality of life. Conclusions: A new awareness of the need for prevention of frailty and cognitive decline is extending. Early diagnosis of frailty and functional decline are considered as effective measures against age-related comorbidities.